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APBB1 gene

Known as: APBB1, Fe65, AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING, FAMILY B, MEMBER 1 
National Institutes of Health

Related topics

Related topics

2 relations
APBB1 protein, humanAPBB1IP gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
The Amyloid Precursor Protein Intracellular Domain-Fe65 Multiprotein Complexes: A Challenge to the Amyloid Hypothesis for Alzheimer's Disease?
Since its proposal in 1994, the amyloid cascade hypothesis has prevailed as the mainstream research subject on the molecular… 
2010
2010
Dab1 binds to Fe65 and diminishes the effect of Fe65 or LRP1 on APP processing
Fe65 and Dab1 are adaptor proteins that interact with the cytoplasmic domain of amyloid precursor protein (APP) via… 
2009
2009
The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation.
FE65 is expressed predominantly in the brain and interacts with the C-terminal domain of beta-amyloid precursor protein (APP). We… 
2007
2007
Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity
Alzheimer's disease (AD) is characterized by neurofibrillary tangles and extracellular plaques, which consist mainly of β‐amyloid… 
2005
2005
Endoproteolytic Cleavage of FE65 Converts the Adaptor Protein to a Potent Suppressor of the sAPPα Pathway in Primates*
Adaptor protein FE65 (APBB1) specifically binds to the intracellular tail of the type I transmembrane protein, β-amyloid… 
2003
2003
Real-time PCR quantitation of FE65 a β-amyloid precursor protein-binding protein after traumatic brain injury in rats
In cases of traumatic brain injury (TBI) in which the patient survived for only a short period of time and was without… 
2003
2003
The neuronal adaptor protein Fe65 is phosphorylated by mitogen-activated protein kinase (ERK1/2)
2003
2003
Real-time PCR quantitation of FE65 a beta-amyloid precursor protein-binding protein after traumatic brain injury in rats.
In cases of traumatic brain injury (TBI) in which the patient survived for only a short period of time and was without… 
Highly Cited
1999
Highly Cited
1999
A Single Point Mutation in a Group I WW Domain Shifts Its Specificity to That of Group II WW Domains*
WW domains can be divided into three groups based on their binding specificity. By random mutagenesis, we switched the… 
1999
1999
Alternatively spliced isoforms of FE65 serve as neuron‐specific and non‐neuronal markers
FE65 is predominantly expressed in brain and is especially rich in the regions with the highest densities of neurons. The FE65… 
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