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AP5346

National Institutes of Health

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ProLindac

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2007
2007
Molecular and cellular effects of AP5346, a novel DACH-platinum linked polymer-compound, compared to oxaliplatin and cisplatin in a panel of human cancer cell lines
C105 Background: AP5346 comprises a novel hydrophilic biocompatible copolymer which acts as a macromolecular carrier, combined… 
2006
2006
Pharmaceutical development, quality control, stability and compatibility of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum antineoplastic agent AP5346.
AP5346 is a low molecular weight polymer-conjugated platinum antineoplastic agent. The lyophilized drug product has completed a… 
2004
2004
606 Phase I and pharmacological study of AP5346, an HPMA copolymer-linked DACH platinum therapeutic, in patients with solid progressive tumors
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