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AP-3 adaptor complex

Known as: AP-3 adaptor complex location 
A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with… Expand
National Institutes of Health

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2014
2014
Ap-3 有用な2価カチオンが強化され粘度特性が改変された馬鈴薯澱粉の製造(澱粉の構造・物性,一般講演,日本応用糖質科学会平成26年度大会(第63回))
 
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2013
2013
Structural Basis for the Recognition of Tyrosine-based Sorting Signals by the μ3A Subunit of the AP-3 Adaptor Complex*
Background: Tyrosine-based, YXXØ-type signals mediate protein sorting through binding to adaptor μ subunits. Results: X-ray… Expand
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Highly Cited
2008
Highly Cited
2008
Protein networks supporting AP-3 function in targeting lysosomal membrane proteins.
The AP-3 adaptor complex targets selected transmembrane proteins to lysosomes and lysosome-related organelles. We reconstituted… Expand
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2007
2007
C. elegans Disabled is required for cell-type specific endocytosis and is essential in animals lacking the AP-3 adaptor complex
Disabled proteins are a conserved family of monomeric adaptor proteins that in mammals are implicated in the endocytosis of… Expand
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Highly Cited
2006
Highly Cited
2006
BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes.
Mutational analyses have revealed many genes that are required for proper biogenesis of lysosomes and lysosome-related organelles… Expand
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Highly Cited
2004
Highly Cited
2004
Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins
The adaptor protein (AP) 3 adaptor complex has been implicated in the transport of lysosomal membrane proteins, but its precise… Expand
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2000
2000
Trafficking of major histocompatibility complex class II molecules in human B-lymphoblasts deficient in the AP-3 adaptor complex.
The major histocompatibility complex class II subunits (MHC-II) alpha and beta assemble with the invariant chain (Ii) in the… Expand
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Highly Cited
2000
Highly Cited
2000
Abnormal vesicular trafficking in mouse models of Hermansky-Pudlak syndrome.
Hermansky-Pudlak Syndrome (HPS) is a group of related multigenic recessively inherited disorders which causes abnormalities in… Expand
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Highly Cited
1999
Highly Cited
1999
Abnormal expression and subcellular distribution of subunit proteins of the AP-3 adaptor complex lead to platelet storage pool deficiency in the pearl mouse.
The pearl mouse is a model for Hermansky Pudlak Syndrome (HPS), whose symptoms include hypopigmentation, lysosomal abnormalities… Expand
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Highly Cited
1998
Highly Cited
1998
ADP-Ribosylation Factor 1 (ARF1) Regulates Recruitment of the AP-3 Adaptor Complex to Membranes
Small GTP-binding proteins such as ADP- ribosylation factor 1 (ARF1) and Sar1p regulate the membrane association of coat proteins… Expand
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