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AMG531
Known as:
AMG 531
, Amgen Megakaryopoiesis protein 531
A recombinant protein with megakarypoiesis stimulating activity. AMG 531 mimics endogenous thrombopoietin (TPO), directly binding to and activating…
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National Institutes of Health
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Broader (1)
romiplostim
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Romiplostim (AMG531, Nplate®) for Secondary Failure of Platelet Recovery After Allogeneic Stem-Cell Transplantation
C. Calmettes
,
S. Vigouroux
,
R. Tabrizi
,
N. Milpied
2011
Corpus ID: 78631333
Abstract 1994 Romiplostim (Rm), a protein that binds to and stimulates the thrombopoietin receptor, has been shown to increase…
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Review
2007
Review
2007
Review article: pharmacological approaches for the treatment of thrombocytopenia in patients with chronic liver disease and hepatitis C infection
N. Afdhal
,
J. Mchutchison
Alimentary Pharmacology and Therapeutics
2007
Corpus ID: 10166331
Background Patients with chronic liver disease and hepatitis C virus (HCV) frequently experience thrombocytopenia that…
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Review
2007
Review
2007
New therapeutic options for adult chronic immune thrombocytopenic purpura: a brief review
S. Panzer
Vox Sanguinis
2007
Corpus ID: 23077785
Background Patients with chronic immune thrombocytopenic purpura (ITP) only require treatment if they are bleeding, or prior to…
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2007
2007
Evaluation of AMG 531 Safety in Splenectomized (S) and Nonsplenectomized (NS) Patients with Chronic Immune Thrombocytopenic Purpura (ITP) in Two Randomized Placebo-Controlled Phase 3 Studies
R. Lyons
,
J. George
,
+7 authors
J. Nichol
2007
Corpus ID: 79276590
AMG 531 is a novel platelet-stimulating peptibody that stimulates the thrombopoietin (TPO) receptor, and is being studied for its…
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2007
2007
Evaluation of AMG 531 Efficacy in Splenectomized Patients with Chronic Immune Thrombocytopenic Purpura (ITP) in a Randomized Placebo-Controlled Phase 3 Study.
T. Gernsheimer
,
V. Pullarkat
,
+8 authors
J. Nichol
2007
Corpus ID: 221030545
AMG 531 is a novel thrombopoiesis-stimulating peptibody that acts by stimulating the thrombopoietin (TPO) receptor. We report…
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2007
2007
A Comparative Proteomic Analysis of Platelets from Healthy Human Patients and Chronic ITP Patients Receiving AMG 531, a Thrombopoiesis-Stimulating Protein.
J. Sloan
,
J. Coburn
,
A. Bertino
,
V. Wood
,
D. Kuter
2007
Corpus ID: 57945553
AMG 531 is a novel thrombopoiesis-stimulating “peptibody” consisting of an Fc carrier domain linked to 4 identical peptides that…
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2007
2007
AMG 531 for chronic ITP.
S. Tauro
New England Journal of Medicine
2007
Corpus ID: 205039164
n engl j med 356;3 www.nejm.org january 18, 2007 307 is still unknown for carotid stenting. These findings suggest a potential…
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2007
2007
Health-Related Quality of Life (HRQoL) in Patients (Pts) with Chronic Immune Thrombocytopenic Purpura (ITP): Results from Two Placebo-Controlled Phase 3 Studies of AMG 531.
J. George
,
R. Lyons
,
+9 authors
J. Nichol
2007
Corpus ID: 208392367
Pt-reported outcomes (PROs) are important tools for understanding the effects of treatment for various diseases. We developed the…
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2006
2006
Amgen's TPO mimic faces stiff competition
S. Lawrence
Nature Biotechnology
2006
Corpus ID: 10556406
With seemingly novel science, unsatisfactory existing treatment options and a sizeable potential patient population, it’s hard to…
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2006
2006
Platelet Aggregation Analysis of AMG 531 in a Randomized, Placebo-Controlled Study in Healthy Japanese Subjects.
Y. Kumagai
,
T. Fujita
,
+6 authors
J. Nichol
2006
Corpus ID: 78131886
AMG 531 is a novel thrombopoiesis-stimulating peptibody currently being investigated for the treatment of chronic immune…
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