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AMG 655

Known as: AMG-655, AMG655 
National Institutes of Health

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Related topics

1 relation

Broader (1)

conatumumab

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Abstract 2288: Pharmacological inhibition of B-Raf/MEK/ERK signaling suppresses DR5 expression and impairs cancer cell response to DR5 activation-induced apoptosis
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Inhibition of B-Raf/MEK/ERK signaling is an effective… 
2014
2014
Abstract 5429: The combination of Apo2L/Trail and a death receptor 5 agonist antibody leads to enhanced antitumor activity in mouse syngeneic tumor models
Background: Death receptor-5 (DR5, TR2, TRAIL-R2) is a death domain-containing receptor that induces an apoptosis signaling… 
2013
2013
Estratègies terapèutiques dirigides a evitar resistències en adenocarcinoma ductal pancreàtic
L’adenocarcinoma ductal pancreatic (PDAC) es una de les principals causes de mort per cancer. De fet, practicament no hi ha hagut… 
2010
2010
The way forward in treating pancreatic cancer
The statistics are familiar to us all. In the United States, 42,470 men and women will be diagnosed with, and 35,240 men and… 
2009
2009
A phase Ib/II trial of AMG 655 and panitumumab (pmab) for the treatment (tx) of metastatic colorectal cancer (mCRC): Safety results.
4130^ Introduction: Pmab is a fully human antibody targeting the epidermal growth factor receptor that is approved as monotherapy… 
2008
2008
AMG 655, a monoclonal antibody agonist directed against Death Receptor 5, induces apoptosis in human colon carcinoma cell lines and its therapeutic potential is enhanced in combination with…
1326 Death Receptor 5 (DR5), a member of the tumor necrosis factor family of receptors, can transduce an apoptotic signal… 
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