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AMG-3969

National Institutes of Health

Papers overview

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2014
2014
A nonracemic synthesis of the glucokinase-glucokinase regulatory protein disruptor AMG-3969 (5) is reported. Key features of the… 
2014
2014
We have recently reported a novel approach to increase cytosolic glucokinase (GK) levels through the binding of a small molecule… 
2014
2014
In the previous report , we described the discovery and optimization of novel small molecule disruptors of the GK-GKRP… 
Highly Cited
2013
Highly Cited
2013
Glucose homeostasis is a vital and complex process, and its disruption can cause hyperglycaemia and type II diabetes mellitus…