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AM 36

Known as: AM-36, AM36 compound 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

CNSB 002

Broader (1)

Piperazines

Papers overview

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2008
2008
Pharmacokinetics and brain uptake of AM‐36, a novel neuroprotective agent, following intravenous administration to rats
The plasma pharmacokinetics and brain uptake of the novel neuroprotective agent AM‐36 (1‐(2‐(4‐chlorophenyl)‐2‐hydroxy)ethyl‐4‐(3… 
2006
2006
AM‐36 modulates the neutrophil inflammatory response and reduces breakdown of the blood brain barrier after endothelin‐1 induced focal brain ischaemia
Following transient focal stroke, rapid accumulation and activation of neutrophils in the ischaemic region is deleterious due to… 
2004
2004
Sodium channel blocking activity of AM-36 and sipatrigine (BW619C89): in vitro and in vivo evidence
2003
2003
AM-36, a novel neuroprotective agent, profoundly reduces reactive oxygen species formation and dopamine release in the striatum of conscious rats after endothelin-1-induced middle cerebral artery…
2001
2001
Incorporation of sodium channel blocking and free radical scavenging activities into a single drug, AM‐36, results in profound inhibition of neuronal apoptosis
AM‐36 is a novel neuroprotective agent incorporating both antioxidant and Na+ channel blocking actions. In cerebral ischaemia… 
2001
2001
Investigation of AM-36: a novel neuroprotective agent.
SUMMARY 1. The neurochemical sequelae following cerebral ischaemia are complex, involving excess release of excitatory amino… 
Review
2001
Review
2001
Investigation Of AM‐36: A Novel Neuroprotective Agent
1. The neurochemical sequelae following cerebral ischaemia are complex, involving excess release of excitatory amino acids… 
2000
2000
A novel, rapid, computerised method for quantitation of neuronal damage in a rat model of stroke
Highly Cited
1999
Highly Cited
1999
Delayed treatment with AM-36, a novel neuroprotective agent, reduces neuronal damage after endothelin-1-induced middle cerebral artery occlusion in conscious rats.
BACKGROUND AND PURPOSE AM-36 is a novel arylalkylpiperazine with combined antioxidant and Na(+) channel blocking actions… 
1948
1948
New North American chiggers, Acarina, Trombiculidae.
Larvae, in life, orange, broad-elliptical. Size: Length, 500 to 643; width, 316 to 408. Capitulum (Fig. 1, B): Chelicerae… 
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