ALX 5407

 
National Institutes of Health

Papers overview

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2018
2018
Protective Effects of a Polyphenol-Rich Extract from Syzygium cumini (L.) Skeels Leaf on Oxidative Stress-Induced Diabetic Rats
Syzygium cumini (L.) Skeels has been reported to exert anti-inflammatory and cardiometabolic activities due to its high content… Expand
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2017
2017
"114"-Type Nitrides LnAl(Si4-x Alx )N7 Oδ with Unusual [AlN6 ] Octahedral Coordination.
Aluminum-nitrogen six-fold octahedral coordination, [AlN6 ], is unusual and has only been seen in the high-pressure rocksalt-type… Expand
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2010
2010
Phosphorylation at serine 318 is not required for inhibition of T cell activation by ALX.
The activation of T cells and the initiation of an immune response is tightly controlled by both positive and negative regulators… Expand
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2008
2008
Differential effects of spinally applied glycine transporter inhibitors on nociception in a rat model of neuropathic pain
Changes in glycinergic neurotransmission in the spinal cord dorsal horn are critically involved in the development of… Expand
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2007
2007
Contribution of endogenous glycine and d-serine to excitotoxic and ischemic cell death in rat cerebrocortical slice cultures.
N-methyl-D-aspartate (NMDA) receptors, whose activation requires glycine site stimulation, play crucial roles in various… Expand
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2006
2006
WPO, COV and IIA bargaining solutions
The class of bargaining solutions that are defined on the domain of finite sets of alternatives and satisfy Weak Pareto… Expand
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Highly Cited
2005
Highly Cited
2005
Modulators of the glycine site on NMDA receptors, d-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia
RationaleSchizophrenia is characterized by disturbances in sensorimotor gating and attentional processes, which can be measured… Expand
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Highly Cited
2001
Highly Cited
2001
ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter.
High-affinity glycine transport in neurons and glial cells is a primary means of inactivating synaptic glycine. We have… Expand
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1999
1999
Reduced nociceptive responses in mice with alloxan induced hyperglycemia after garlic (Allium sativum Linn.) treatment.
Administration of ethanol (95%) extract (45 mg/kg body wt/day for 28 days) of garlic (A. sativum) to alloxan induced diabetic… Expand
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1988
1988
Secretin-induced exocrine secretion in perfused pancreas isolated from diabetic rats.
Exocrine secretory function in response to 10 pM to 10 nM synthetic secretin was evaluated in perfused pancreas isolated from… Expand
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