AKT1S1 wt Allele

Known as: AKT1 Substrate 1 (Proline-Rich) wt Allele, PRAS40, MGC2865 
Human AKT1S1 wild-type allele is located in the vicinity of 19q13.33 and is approximately 9 kb in length. This allele, which encodes proline-rich… (More)

Topic mentions per year

Topic mentions per year

2003-2017
0102020032017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Cytosolic compartmentalization through liquid-liquid unmixing, such as the formation of RNA granules, is involved in many… (More)
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2011
2011
Hyperglycemia induces a wide array of signaling pathways in the kidney that lead to hypertrophy and matrix expansion, eventually… (More)
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Highly Cited
2007
Highly Cited
2007
The heterotrimeric mTORC1 protein kinase nucleates a signaling network that promotes cell growth in response to insulin and… (More)
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Highly Cited
2007
Highly Cited
2007
Insulin stimulates protein synthesis and cell growth by activation of the protein kinases Akt (also known as protein kinase B… (More)
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Highly Cited
2007
Highly Cited
2007
Mammalian target of rapamycin (mTOR) functions in two distinct signaling complexes, mTORC1 and mTORC2. In response to insulin and… (More)
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Highly Cited
2007
Highly Cited
2007
The proline-rich Akt substrate of 40 kilodaltons (PRAS40) was identified as a raptor-binding protein that is phosphorylated… (More)
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Highly Cited
2007
Highly Cited
2007
Signaling through the mammalian target of rapamycin complex 1 (mTORC1) is positively regulated by amino acids and insulin. PRAS40… (More)
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Highly Cited
2007
Highly Cited
2007
TOR (Target of Rapamycin) is a highly conserved protein kinase and a central controller of cell growth. TOR is found in two… (More)
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2007
2007
Malignant melanoma is the most invasive and deadly form of skin cancer with no effective therapy to treat advanced disease… (More)
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Highly Cited
2003
Highly Cited
2003
Akt (also called protein kinase B) is one of the major downstream targets of the phosphatidylinositol 3-kinase pathway. This… (More)
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