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AKT1S1 wt Allele

Known as: AKT1 Substrate 1 (Proline-Rich) wt Allele, PRAS40, MGC2865 
Human AKT1S1 wild-type allele is located in the vicinity of 19q13.33 and is approximately 9 kb in length. This allele, which encodes proline-rich… 
National Institutes of Health

Related topics

Related topics

2 relations
19q13.33Signal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Trimedazidine alleviates pulmonary artery banding-induced acute right heart dysfunction and activates PRAS40 in rats
The molecular mechanism underlying acute right heart failure (RHF) is poorly understood. We used pulmonary artery banding (PAB… 
2014
2014
Proline-rich Akt substrate of 40 kDa (PRAS40): A new modulator and target of insulin action. Characterization of the function of PRAS40 in Akt- and mammalian target of rapamycin complex 1 (mTORC1…
Nach neusten Schatzungen wird die weltweite Pravalenz von Diabetes von 366 Millionen Betroffenen im Jahr 2011 auf 552 Millionen… 
2013
2013
mTOR/PRAS40 interaction
Signals from growth factors, nutrients, energy status, as well as many stressors impinge upon the mechanistic target of rapamycin… 
Review
2012
Review
2012
Role of PRAS 40 in Akt and mTOR signaling in health and disease
Wiza C, Nascimento EB, Ouwens DM. Role of PRAS40 in Akt and mTOR signaling in health and disease. Am J Physiol Endocrinol Metab… 
2012
2012
Combined Blockade of PI3K/AKT and EGFR/HER3 Enhances Anti-Tumor Activity in Triple Negative Breast Cancer
2011
2011
microRNA-21 ORCHESTRATES HIGH GLUCOSE-INDUCED SIGNALS TO TORC 1 FOR RENAL CELL PATHOLOGY IN DIABETES
Hyperglycemia induces a wide array of signaling pathways in the kidney that lead to hypertrophy and matrix expansion, eventually… 
2010
2010
correlates with PRAS40 phosphorylation 2
2010
2010
Regulation of mTOR complex 1 in response to growth factors and nutrients
In multicellular organisms, cells ensure the simultaneous availability of growth factors and nutrients before they invest in… 
2007
2007
Deregulates Apoptosis in Malignant Melanoma
Malignant melanoma is the most invasive and deadly form of skin cancer with no effective therapy to treat advanced disease… 
Review
2005
Review
2005
IDENTIFICATION OF P 122 RHOGAP ( D ELETED IN L IVER C ANCER-1 ) SERINE-322 AS A SUBSTRATE FOR PROTEIN KINASE B AND RSK IN INSULIN-STIMULATED CELLS
Protein kinase B (Akt) plays an essential role in the actions of insulin, cytokines and growth factors, although the substrates… 
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