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AJUBA gene

Known as: MGC15563, AJUBA, Ajuba LIM Protein Gene 
This gene plays a role in the assembly of protein complexes, which are involved in a number of cellular processes.
National Institutes of Health

Related topics

Related topics

5 relations
AJUBA protein, humanMitosisSignal TransductionStress Response Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
LIM Protein Ajuba associates with the RPA complex through direct cell cycle-dependent interaction with the RPA70 subunit
DNA damage response pathways are essential for genome stability and cell survival. Specifically, the ATR kinase is activated by… 
2015
2015
A hydrogel-endothelial cell implant mimics infantile hemangioma: modulation by survivin and the Hippo pathway
Microvascular endothelial cells cultured in three-dimensional hydrogel scaffolds form a network of microvessel structures when… 
2014
2014
Aurora-A kinase-inactive mutants disrupt the interaction with Ajuba and cause defects in mitotic spindle formation and G2/M phase arrest in HeLa cells
Aurora-A is a centrosome-localized serine/threonine kinase that is overexpressed in multiple human cancers. We previously… 
2014
2014
A novel mechanism for activation of Aurora-A kinase by Ajuba.
2013
2013
Hold on tightly
Signaling regulated by Rho small GTPases plays a pivotal role in cell migration, cell attachment to substratum or to their… 
Highly Cited
2010
Highly Cited
2010
LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling
Corepressors play an essential role in nuclear receptor-mediated transcriptional repression. In general, corepressors directly… 
2009
2009
Ajuba: a new microtubule‐associated protein that interacts with BUBR1 and Aurora B at kinetochores in metaphase
Background information. The role of the LIM‐domain‐containing protein Ajuba was initially described in cell adhesion and… 
2009
2009
Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A
Entry into mitosis requires the activation of mitotic kinases, including Aurora A and Polo-like kinase 1 (Plk1). Increased levels… 
2008
2008
Ajuba negatively regulates the Wnt signaling pathway by promoting GSK-3beta-mediated phosphorylation of beta-catenin.
The Wnt signaling pathway is essential for embryonic development and carcinogenesis. Upon Wnt stimulation, beta-catenin is… 
Highly Cited
2002
Highly Cited
2002
The Amino Terminus of the Glial Glutamate Transporter GLT-1 Interacts with the LIM Protein Ajuba
We have identified a cytoplasmic LIM protein, Ajuba, which interacts with the amino terminus of GLT-1, the most abundant plasma… 
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