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AGN 193109

Known as: AGN-193109 
 
National Institutes of Health

Papers overview

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2006
2006
Geranylgeranyl pyrophosphate (GGPP) and geranylgeraniol (GGOH) are used for the prenylation of GTP binding proteins and can… Expand
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2003
2003
  • J. Zhou, D. Kochhar
  • Birth defects research. Part A, Clinical and…
  • 2003
  • Corpus ID: 7617294
BACKGROUND Eye malformations induced by vitamin A deficiency (VAD) during pregnancy is a major part of the VAD syndrome. But the… Expand
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2002
2002
Potential pharmacological applications in the areas of oncology, dermatology, diabetes, and atherosclerosis of synthetic analogs… Expand
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2001
2001
The synthetic retinoid AGN 193109 is a potent pan retinoic acid receptor (RAR) antagonist. Treatment of pregnant mice with a… Expand
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Highly Cited
2000
Highly Cited
2000
Despite its potent biologic effect on human sebocytes, 13-cis retinoic acid exhibits low binding affinity for cellular retinoic… Expand
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1999
1999
A series of high affinity retinoic acid receptor (RAR) antagonists were prepared based upon the known antagonist AGN 193109 (2… Expand
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1999
1999
Retinoids are important regulators of epithelial differentiation. AGN 193109 is a high-affinity antagonist and inverse agonist… Expand
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1997
1997
It has been proposed that RAR gamma, the major retinoic acid receptor (RAR) subtype in skin, mediates retinoid-induced skin… Expand
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1996
1996
AGN 193109 was recently identified as a potent retinoic acid receptor (RAR) antagonist in vitro. The purpose of the present study… Expand
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1996
1996
Vitamin A and its derivatives (retinoids) have been known to cause premature epiphyseal closure in humans as an unwanted side… Expand
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