AGI-6780

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2013-2016
0520132016

Papers overview

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2017
2017
Neomorphic mutation R140Q in the metabolic enzyme isocitrate dehydrogenase 2 (IDH2) is found to be a driver mutation in cancers… (More)
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Review
2016
Review
2016
Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to α-ketoglutarate (α-KG). Genetic gain-of-function… (More)
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Highly Cited
2013
Highly Cited
2013
A number of human cancers harbor somatic point mutations in the genes encoding isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2… (More)
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2013
2013
1. Warburg, O., Posener, K. & negelein, E. Biochem. Z. 152, 309–344 (1924). 2. Hanahan, D. & Weinberg, R.A. Cell 144, 646–674… (More)
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2013
2013
 
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2013
2013
 
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2013
2013
 
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2013
2013
Somatic mutations in genes encoding isocitrate dehydrogenase isoforms IDH1 and IDH2 have recently been found in 50–80% of human… (More)
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2013
2013
Somatic mutations in genes encoding isocitrate dehydrogenase isoforms IDH1 and IDH2 have recently been found in 50–80% of human… (More)
Is this relevant?
2013
2013
Somatic mutations in genes encoding isocitrate dehydrogenase isoforms IDH1 and IDH2 have recently been found in 50–80% of human… (More)
Is this relevant?