AGI-6780
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
The introduction of proteasome inhibitors (PIs) into the clinic has transformed the treatment of patients affected by multiple…
Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to α-ketoglutarate. This process leads to NADPH…
Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to α-ketoglutarate (α-KG). Genetic gain-of-function…
Somatic point mutations in isocitrate dehydrogenase 1/2 (IDH1/2) confer a gain-of-function in cancer cells resulting in the…
Somatic mutations in genes encoding isocitrate dehydrogenase isoforms IDH1 and IDH2 have recently been found in 50–80% of human…
Somatic mutations in genes encoding isocitrate dehydrogenase isoforms IDH1 and IDH2 have recently been found in 50–80% of human…
Somatic mutations in genes encoding isocitrate dehydrogenase isoforms IDH1 and IDH2 have recently been found in 50–80% of human…
Somatic mutations in genes encoding isocitrate dehydrogenase isoforms IDH1 and IDH2 have recently been found in 50–80% of human…