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AG 331

Known as: AG-331 
 
National Institutes of Health

Papers overview

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2009
2009
We have reported that noncytotoxic concentrations of 3′-azido-3′-deoxythymidine (AZT) increase the cytotoxicity of ICI Dl694, a… Expand
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2007
2007
  • 2007
  • Corpus ID: 21484601
yield and quality. Applying combinations of agrichemicals is an efficient practice with known benefits. Producers may reduce the… Expand
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2004
2004
AG-331 {N6[4-(N-morpholinosulfonyl)benzyl]-N6-methyl-2,6-diamino-benz[cd]indole glucuronate} is a novel lipophilic thymidylate… Expand
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2003
2003
Thymidylate synthase (TS), a key cancer chemotherapeutic target, catalyzes the conversion of deoxyuridylate to thymidylate. TS… Expand
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1995
1995
The patterns of DNA fragmentation were evaluated following a brief exposure (2 h) of the human ileocecal adenocarcinoma cell line… Expand
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1995
1995
The effects of de novo dTMP inhibition by N-(5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N- methylamino]-2- thenoyl)-L… Expand
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1995
1995
Inhibition of thymidylate synthase (TS) may increase incorporation of thymidine analogues into DNA, leading to increased… Expand
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1995
1995
A reversed-phase isocratic high-performance liquid chromatographic method has been developed for the determination of AG-331, a… Expand
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1994
1994
AG-331, a water-soluble glucuronate salt of a potential anticancer drug, was synthesized using a technology described as "Protein… Expand
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Review
1993
Review
1993
Molecular modeling techniques and a knowledge of thymidylate synthase protein structure have assisted in the development of… Expand
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