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AFTPH gene

Known as: aftiphilin, FLJ23793, FLJ20080 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin
Neurotensin (NT) triggers signaling in human colonic epithelial cells by activating the G protein-coupled receptor, the… 
2015
2015
MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis.
Ulcerative colitis (UC) and Crohn's Disease (CD) are the two most common forms of Inflammatory Bowel Diseases (IBD) marked by… 
Highly Cited
2014
Highly Cited
2014
Neurotensin—regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis
  • Gut
  • 2014
  • Corpus ID: 14725046
Objective Neurotensin (NT) mediates colonic inflammation through its receptor neurotensin receptor 1 (NTR1). NT stimulates miR… 
2012
2012
AP-1 clathrin adaptor and CG8538/Aftiphilin are involved in Notch signaling during eye development in Drosophila melanogaster
Clathrin adaptor protein complex-1 (AP-1) and its accessory proteins play a role in the sorting of integral membrane proteins at… 
Highly Cited
2010
Highly Cited
2010
Strain Differences in Stress Responsivity Are Associated with Divergent Amygdala Gene Expression and Glutamate-Mediated Neuronal Excitability
Stress is a major risk factor for numerous neuropsychiatric diseases. However, susceptibility to stress and the qualitative… 
2008
2008
Aftiphilin and gamma-synergin are required for secretagogue sensitivity of Weibel-Palade bodies in endothelial cells.
Formation of secretory organelles requires the coupling of cargo selection to targeting into the correct exocytic pathway… 
2005
2005
The aftiphilin/p200/gamma-synergin complex.
Aftiphilin is a protein that was recently identified in database searches for proteins with motifs that interact with AP-1 and… 
2005
2005
Aftiphilin is a component of the clathrin machinery in neurons
Highly Cited
2004
Highly Cited
2004
Definition of the Consensus Motif Recognized by γ-Adaptin Ear Domains*
The heterotetrameric adaptor complex 1 (AP-1) and the monomeric Golgi-localized, γ ear-containing, Arf-binding (GGA) proteins are… 
2004
2004
Definition of the consensus motif recognized by gamma-adaptin ear domains.
The heterotetrameric adaptor complex 1 (AP-1) and the monomeric Golgi-localized, gamma ear-containing, Arf-binding (GGA) proteins… 
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