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AFAP1 gene

Known as: AFAP, 110-KD, AFAP1, AFAP110 
National Institutes of Health

Related topics

Related topics

1 relation
actin filament-associated protein, 110 kDa

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Expression analysis of AFAP1-AS1 and AFAP1 in breast cancer.
Long non-coding RNAs (lncRNA) constitute a significant percentage of RNAs with no translation to proteins. Their participation in… 
2016
2016
Colorectal Adenomatous Polyposis: Heterogeneity of Susceptibility Gene Mutations and Phenotypes in a Cohort of Italian Patients.
AIMS Colorectal adenomatous polyposis entailing cancer predisposition is caused by constitutional mutations in different genes… 
2015
2015
AFAP1 Is a Novel Downstream Mediator of TGF-β1 for CCN2 Induction in Osteoblasts
Background CCN2 acts as an anabolic growth factor to regulate osteoblast differentiation and function. CCN2 is induced by TGF-β1… 
2012
2012
Clinical and molecular features of attenuated adenomatous polyposis in northern Italy
BackgroundAttenuated familial adenomatous polyposis (AFAP) is characterized by the presence of 10–99 colorectal adenomas. The… 
2008
2008
Germline hypermethylation of the APC promoter is not a frequent cause of familial adenomatous polyposis in APC/MUTYH mutation negative families
Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome predisposing to colorectal cancer and affects 1 in 5–10… 
2007
2007
MYH, OGG1, MTH1, and APC alterations involved in the colorectal tumorigenesis of Korean patients with multiple adenomas
This study was done to characterize base excision repair (BER) genes and adenomatous polyposis coli (APC) alterations in the… 
2000
2000
The carboxy terminus of AFAP-110 modulates direct interactions with actin filaments and regulates its ability to alter actin filament integrity and induce lamellipodia formation.
The actin filament-associated protein AFAP-110 is an SH2/SH3 binding partner for Src. AFAP-110 contains several protein-binding… 
1998
1998
Formation of a stable src–AFAP‐110 complex through either an amino‐terminal or a carboxy‐terminal SH2‐binding motif
The actin‐filament–associated protein (AFAP‐110) forms a stable complex with activated variants of the Pp60c‐src (Src) non… 
Highly Cited
1998
Highly Cited
1998
Src can regulate carboxy terminal interactions with AFAP-110, which influence self-association, cell localization and actin filament integrity
The SH2 and SH3 binding partner AFAP-110 is a tyrosine phosphorylated substrate of Src. AFAP-110 has been hypothesized to link… 
1997
1997
The integrity of the SH3 binding motif of AFAP-110 is required to facilitate tyrosine phosphorylation by, and stable complex formation with, Src
The actin filament-associated protein AFAP-110 forms a stable complex with activated variants of Src in chick embryo fibroblast… 
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