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AEOL 10150

Known as: AEOL-10150, AEOL10150 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Metalloporphyrins

Papers overview

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2020
2020
Identifying Circulating and Lung Tissue Cytokines Associated with Thoracic Irradiation and AEOL 10150 Treatment in a Nonhuman Primate Model
Inflammatory cytokines have been suggested to play important roles in radiation-induced lung injury (RILI). Identifying… 
2015
2015
Dose Optimization Study of AEOL 10150 as a Mitigator of Radiation-Induced Lung Injury in CBA/J Mice
AEOL 10150 is a catalytic metalloporphyrin superoxide dismutase mimic being developed as a medical countermeasure for radiation… 
2014
2014
A Pilot Study in Rhesus Macaques to Assess the Treatment Efficacy of a Small Molecular Weight Catalytic Metalloporphyrin Antioxidant (AEOL 10150) in Mitigating Radiation-induced Lung Damage
AbstractThe objective of this pilot study was to explore whether administration of a catalytic antioxidant, AEOL 10150… 
2014
2014
Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects.
2010
2010
Abstract 5546: Improved gastrointestinal repair post irradiation with AEOL 10150
Background Gastrointestinal toxicity, often manifested as ulceration and diarrhoea (mucositis) occurs following exposure to… 
2010
2010
AEOL10150: A Novel Therapeutic For Rescue Treatment Following Toxic Gas Lung Injury
Background— New therapeutics designed as rescue treatments following toxic gas injury such as chlorine (Cl 2 ) are an emerging… 
2007
2007
Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation.
Review
2006
Review
2006
AEOL-10150 (Aeolus).
AEOL-10150, a small-molecule antioxidant analogous to the catalytic site of superoxide dismutase, is under development by Aeolus… 
2005
2005
Antioxidant therapeutic interventions Systemic antioxidant capacity and antioxidant vitamins
Correspondence: Irfan Rahman Department of Environmental Medicine, Division of Lung Biology and Disease, University of Rochester… 
2003
2003
Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury.
Hemorrhage results in excessive production of superoxide that is associated with severe lung injury. We examined whether the… 
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