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AEOL 10150

Known as: AEOL-10150, AEOL10150 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
PURPOSE Apoptosis in irradiated normal lung tissue has been observed several weeks after radiation. However, the signaling… Expand
2011
2011
New therapeutics designed as rescue treatments after toxic gas injury such as from chlorine (Cl(2)) are an emerging area of… Expand
Highly Cited
2010
Highly Cited
2010
Sulfur mustard (bis-2-(chloroethyl) sulfide; SM) is a highly reactive vesicating and alkylating chemical warfare agent. A SM… Expand
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Review
2010
Review
2010
The most efficacious Mn(III) porphyrinic (MnPs) scavengers of reactive species have positive charges close to the Mn site… Expand
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Highly Cited
2007
Highly Cited
2007
PURPOSE To determine whether administration of a catalytic antioxidant, Mn(III) tetrakis(N,N'-diethylimidazolium-2-yl) porphyrin… Expand
Review
2006
Review
2006
Reactive oxygen species, either directly or via the formation of lipid peroxidation products, may play a role in enhancing… Expand
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Review
2006
Review
2006
  • R. Orrell
  • Current opinion in investigational drugs
  • 2006
  • Corpus ID: 36608511
AEOL-10150, a small-molecule antioxidant analogous to the catalytic site of superoxide dismutase, is under development by Aeolus… Expand
Highly Cited
2004
Highly Cited
2004
The process of human islet isolation triggers a cascade of stressful events in the islets of Langerhans involving activation of… Expand
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Highly Cited
2002
Highly Cited
2002
The most commonly used technical approach to isolate human pancreatic islets intended for allotransplants generates a product… Expand
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Highly Cited
2002
Highly Cited
2002
Oxidative stress is a major source of injury from cerebral ischemia and reperfusion. We hypothesized that a catalytic antioxidant… Expand