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ADR 925

Known as: ADR-925 
 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
SIGNIFICANCE Anthracyclines (doxorubicin, daunorubicin, or epirubicin) rank among the most effective anticancer drugs, but their… Expand
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2013
2013
Dexrazoxane (DEX) is the only clinically used drug effective against anthracycline-induced cardiotoxicity and extravasation… Expand
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2009
2009
Background:Dexrazoxane (DEX, ICRF-187) is the only clinically approved cardioprotectant against anthracycline cardiotoxicity. It… Expand
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2007
2007
Dexrazoxane is a cardioprotective antioxidant that is clinically used to reduce the cardiotoxicity of the chemotherapeutic drug… Expand
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2003
2003
The clinically approved cardioprotective agent dexrazoxane (ICRF-187) and two of its hydrolyzed metabolites (a one-ring open form… Expand
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2003
2003
PurposeThe study was undertaken to determine the metabolism of dexrazoxane (ICRF-187) to its one-ring open hydrolysis products… Expand
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2002
2002
Abstract Purpose. Dexrazoxane is clinically used as a doxorubicin-cardioprotective agent and may act by preventing iron-based… Expand
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Highly Cited
2001
Highly Cited
2001
Abstract.Purpose: To compare the protective effect of dexrazoxane (DRZ) against cardiotoxicity induced by doxorubicin (DXR) and… Expand
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2001
2001
BACKGROUND Recently, we have shown that dexrazoxane (ICRF-187) is an effective antidote against accidental extravasation of… Expand
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Highly Cited
1995
Highly Cited
1995
A series of twelve structurally related bisdioxopiperazines that included ICRF-187 (dexrazoxane), ICRF-159 (razoxane), ICRF-193… Expand
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