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Ablation of the cellular prion protein PrPC leads to a chronic demyelinating polyneuropathy affecting Schwann cells. Neuron… Expand The Adhesion family forms a large branch of the pharmacologically important superfamily of G protein–coupled receptors (GPCRs… Expand Myelin ensheathes axons to allow rapid propagation of action potentials and proper nervous system function. In the peripheral… Expand Adolescent idiopathic scoliosis (AIS) and pectus excavatum (PE) are common pediatric musculoskeletal disorders. Little is known… Expand Type IV collagen activates the cell surface receptor GPR126, an orphan receptor that is crucial for Schwann cell differentiation… Expand Adolescent idiopathic scoliosis (AIS) is the most common pediatric skeletal disease. We previously reported a locus on chromosome… Expand The myelin sheath surrounding axons ensures that nerve impulses travel quickly and efficiently, allowing for the proper function… Expand Significance Adhesion G protein-coupled receptors (GPCRs) are expressed in many developing organs, immune cells, and cancer cells… Expand Morphogenesis of the semicircular canal ducts in the vertebrate inner ear is a dramatic example of epithelial remodelling in the… Expand In peripheral nerves, Schwann cells form the myelin sheath that insulates axons and allows rapid propagation of action potentials… Expand