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ADAM22 gene

Known as: ADAM22, MDC2, A DISINTEGRIN AND METALLOPROTEINASE DOMAIN 22 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Human Miscarriage Is Associated With Dysregulations in Peripheral Blood-Derived Myeloid Dendritic Cell Subsets
Dendritic cells (DC) are critically involved in decisions related to the acceptance or rejection of the foreign fetal antigens by… 
2018
2018
miR-449a Suppresses Tamoxifen Resistance in Human Breast Cancer Cells by Targeting ADAM22
Background/Aims: Most of estrogen receptor positive breast cancer patients respond well initially to endocrine therapies, but… 
2016
2016
Dysfunctional ADAM22 implicated in progressive encephalopathy with cortical atrophy and epilepsy
Objective: To identify the molecular genetic basis of a syndrome characterized by rapidly progressing cerebral atrophy… 
Highly Cited
2012
Highly Cited
2012
Global characterization of the SRC-1 transcriptome identifies ADAM22 as an ER-independent mediator of endocrine-resistant breast cancer.
The development of breast cancer resistance to endocrine therapy results from an increase in cellular plasticity that permits the… 
2008
2008
Type 1 diabetes patients have significantly lower frequency of plasmacytoid dendritic cells in the peripheral blood.
Highly Cited
2006
Highly Cited
2006
TaqMan PCR assay in the control of RNA normalization in human post-mortem brain tissue
2006
2006
ADAM22, Expressed in Normal Brain but not in High-Grade Gliomas, Inhibits Cellular Proliferation via the Disintegrin Domain
OBJECTIVE:To study the expression and function of the brain-specific proteinase deficient disintegrins, ADAM11 and ADAM22 (a… 
Highly Cited
2005
Highly Cited
2005
Ataxia and peripheral nerve hypomyelination in ADAM22-deficient mice
BackgroundADAM22 is a member of the ADAM gene family, but the fact that it is expressed only in the nervous systems makes it… 
Highly Cited
2000
Highly Cited
2000
Monocyte-Derived CD1a+ and CD1a− Dendritic Cell Subsets Differ in Their Cytokine Production Profiles, Susceptibilities to Transfection, and Capacities to Direct Th Cell Differentiation1
We describe a phenotypically and functionally novel monocyte-derived dendritic cell (DC) subset, designated mDC2, that lacks IL… 
Highly Cited
1998
Highly Cited
1998
Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain.
Cellular disintegrins are a family of membrane-anchored proteins structurally related to snake venom disintegrins, and are… 
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