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AD2765

National Institutes of Health

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Sphingomyelins

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2005
2005
A lipid analogue that inhibits sphingomyelin hydrolysis and synthesis, increases ceramide, and leads to cell death Published, JLR Papers in Press, September 8, 2005. DOI 10.1194/jlr.M500136-JLR200
We report the synthesis and characterization of a novel thiourea derivative of sphingomyelin (AD2765). In vitro assays using pure… 
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