ACLY gene

Known as: CLATP, ATP CITRATE LYASE, ATP citrate synthase 
This gene is involved in acetyl-CoA metabolism.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
0102019922017

Papers overview

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2016
2016
Macrophage activation/polarization to distinct functional states is critically supported by metabolic shifts. How polarizing… (More)
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2014
2014
De novo lipogenesis is activated in most cancers and several lipogenic enzymes have been implicated as therapeutic targets. Here… (More)
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2012
2012
We previously demonstrated that high-fat diet (HFD)-induced hepatic lipid accumulation is more severe in BALB/c mice than in… (More)
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Highly Cited
2011
Highly Cited
2011
Despite the role of aerobic glycolysis in cancer, recent studies highlight the importance of the mitochondria and biosynthetic… (More)
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Highly Cited
2011
Highly Cited
2011
Cardiovascular disease remains the leading cause of mortality in westernized countries, despite optimummedical therapy to reduce… (More)
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2010
2010
ATP-citrate lyase (ACLY) catalyzes the conversion of citrate and CoA into acetyl-CoA and oxaloacetate, coupled with the… (More)
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2010
2010
Glioblastomas, the most malignant type of glioma, are more glycolytic than normal brain tissue. Robust migration of glioblastoma… (More)
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2009
2009
The purpose of this study was to investigate variations in hepatic regulation of metabolism during the dry period, after… (More)
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Highly Cited
2002
Highly Cited
2002
DNA copy number gains and amplifications at 17q are frequent in gastriccancer, yet systematic analyses of the 17q amplicon have… (More)
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1992
1992
Seven genes and two anonymous markers were mapped to a single linkage group on rat chromosome 10 using progeny of an F2… (More)
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