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ACI, Rat Strain

Known as: ACI 
Median survival 113 weeks in males, 108 weeks in females. Spontaneous tumors 46% testes, 16% adrenal, 5% pituitary, 6% skin and ear duct and fewer of… 
National Institutes of Health

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Clinical Data Interchange Standards Consortium Terminology

Papers overview

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2011
2011
Abstract 1318: Progesterone promotes estrogen induced mammary carcinogenesis through activation of RANKL
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL Ovarian hormones estrogen and progesterone play a vital… 
2010
2010
Abstract 1887: Distinct molecular targets of blueberry and black raspberry in breast cancer prevention
We previously demonstrated protection with berries in diet, against estrogen-induced ACI rat mammary tumorigenesis, by inhibition… 
Highly Cited
2004
Highly Cited
2004
Genetic Determination of Susceptibility to Estrogen-Induced Mammary Cancer in the ACI Rat
Hormonal, genetic, and environmental factors play major roles in the complex etiology of breast cancer. When treated continuously… 
2001
2001
Predominant 4-hydroxylation of estradiol by constitutive cytochrome P450s in the female ACI rat liver.
The ACI rat is extremely sensitive to estrogens as mammary carcinogens, whereas the Sprague-Dawley strain is relatively resistant… 
1995
1995
IN VIVO MICROSCOPIC ASSESSMENT OF HEPATIC MICROCIRCULATION DURING LIVER ALLOGRAFT REJECTION IN THE RAT
The hemodynamic alterations in hepatic microvasculature during acute rejection of rat liver allografts was studied using in vivo… 
1995
1995
Monitoring for Engraftment following Rat Orthotopic Liver Transplantation by in Vitro Amplification of Y-Chromosome Gene Using Polymerase Chain Reaction
The polymerase chain reaction (PCR) using primers specific for the rat Y-chromosome gene made it possible to distinguish a very… 
1994
1994
Development of pigmented scales on rat skin: relation to age, sex, strain, and hormonal effect.
Development of brownish scales on the skin was examined in seven inbred strains of laboratory rats, Rattus norvegicus (F344, WM… 
1987
1987
STUDY ON STRAIN DIFFERENCE AND IMMUNOLOGICAL BACKGROUND OF 1, 2-DIMETHYLHYDRAZINE-INDUCED COLON TUMORS IN THE RAT
Rats of three strains, ACI, Buffalo and Wistar, were treated with 1, 2-dimethylhydrazine (DMH) 20 mg/kg/week, serially for nine… 
1986
1986
Urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)-nitrosamine in an analbuminemic congenic strain of rats with an ACI genetic background.
An analbuminemic congenic strain of rats originating from ACI (ACI-alb) rats was established. The rats were found to be highly… 
1966
1966
Relations between area and desoxyribonucleic acid content of the mammary gland in mice.
To the Editors: The mammary gland area(MGA)as determined by the whole mount preparation, that is, the area bounded by a line… 
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