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ABT 898

Known as: ABT-898, ABT898 
 
National Institutes of Health

Papers overview

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2016
2016
Chronic effects of an anti-angiogenic thrombospondin-1 mimetic peptide, ABT-898, on female mouse reproductive outcomes
BackgroundAngiogenesis is an essential process in endometriosis disease progression. Earlier, we demonstrated that anti… Expand
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2016
2016
Additional file 2: Figure S2. of Chronic effects of an anti-angiogenic thrombospondin-1 mimetic peptide, ABT-898, on female mouse reproductive outcomes
Whole mount immunofluorescence for the pan endothelial cell marker CD31 in endometriotic lesions, uterus and ovary. (A… Expand
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2015
2015
Thrombospondin peptide ABT-898 inhibits inflammation and angiogenesis in a colitis model.
AIM To evaluate the efficacy of the improved thrombospondin mimetic peptide ABT-898 in a murine model of ulcerative colitis… Expand
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2015
2015
Compatibility of a Novel Thrombospondin-1 Analog with Fertility and Pregnancy in a Xenograft Mouse Model of Endometriosis
Endometriosis is a gynecological disease defined by the growth of endometrium outside of the uterus. Although endometriosis… Expand
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2014
2014
AI-03TARGETING ANGIOGENESIS WITHOUT INCREASING THE STROMAL CELL RESPONSE OR INVASION USING ABT-898, A THROMBOSPONDIN TYPE 1 REPEAT PEPTIDE
Anti-angiogenic therapy is a promising therapeutic approach for highly vascularized tumors including glioblastoma (GBM… Expand
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2012
2012
Thrombospondin-1 (TSP-1) analogs ABT-510 and ABT-898 inhibit prolactinoma growth and recover active pituitary transforming growth factor-β1 (TGF-β1).
Prolactinomas are the most prevalent type of secreting pituitary tumors in humans and generally respond well to a medical therapy… Expand
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2012
2012
Prospective study of thrombospondin-1 mimetic peptides, ABT-510 and ABT-898, in dogs with soft tissue sarcoma.
BACKGROUND Exposure to anti-angiogenic thrombospondin-1 (TSP-1) mimetic peptides (MPs) has resulted in sporadic anti-tumor… Expand
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2011
2011
ABT-898 induces tumor regression and prolongs survival in a mouse model of epithelial ovarian cancer.
Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy and is often not diagnosed until late stages due to its… Expand
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2011
2011
Preclinical Development ABT-898 Induces Tumor Regression and Prolongs Survival in a Mouse Model of Epithelial Ovarian Cancer
Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy and is often not diagnosed until late stages due to its… Expand
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2010
2010
A thrombospondin-mimetic peptide, ABT-898, suppresses angiogenesis and promotes follicular atresia in pre- and early-antral follicles in vivo.
Using a novel in vitro angiogenesis assay, we previously showed that thrombospondin (TSP)-1 has antiangiogenic effects on rat… Expand
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