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ABT 761

Known as: A-85761, ABT-761 
National Institutes of Health

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1 relation

Broader (1)

atreleuton

Papers overview

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2002
2002
Effect of Physicochemical and Formulation Variables on the In Vivo Absorption of ABT-761
ABSTRACT ABT-761 is a 5-lipoxygenase inhibitor developed for the treatment of asthma. The present study was undertaken to… 
2001
2001
ABT-761 (Abbott).
Abbott's ABT-761 is a 5-lipoxygenase inhibitor with 8-fold increased potency over Bay-X-1005 and 150-fold over zileuton [171665… 
1998
1998
Effects of ABT‐761, a Novel 5‐Lipoxygenase Inhibitor, on the Pharmacokinetics of a Single Dose of Ethinyl Estradiol and Levonorgestrel in Healthy Female Volunteers
ABT‐761 is a second‐generation 5‐lipoxygenase inhibitor in clinical development for the treatment of asthma. The effects of ABT… 
Highly Cited
1997
Highly Cited
1997
The effect of ABT-761, a novel 5-lipoxygenase inhibitor, on exercise- and adenosine-induced bronchoconstriction in asthmatic subjects.
Leukotrienes have been implicated in the bronchoconstriction caused by indirect stimuli. In the present study we examined the… 
1997
1997
Effect of mast cell deficiency and leukotriene inhibition on the influx of eosinophils induced by eotaxin
Eosinophils are believed to be important cells in the pathogenesis of asthma and allergic disease. Mast cells and leukotrienes… 
Review
1997
Review
1997
Biosynthesis inhibitors for leukotrienes in bronchial asthma.
This article reviews the literature on the effects of leukotrienes in asthma. In particular, the ability of recently developed… 
1996
1996
5-リポキシゲナーゼ阻害薬 (ABT-761) 投与による血漿中濃度とロイコトリエン産生に対する検討
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