ABT-100

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2009
02420052009

Papers overview

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2009
2009
Farnesyltransferase inhibitors (FTIs), developed as anti-cancer drugs, have the potential to modulate immune responses without… (More)
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Highly Cited
2006
Highly Cited
2006
Progerias are rare genetic diseases characterized by premature aging. Several progeroid disorders are caused by mutations that… (More)
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2005
2005
BACKGROUND Farnesyltransferase inhibitors (FTIs) inhibit the function of Ras, a GTPase involved in carcinogenesis and T cell… (More)
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2005
2005
PURPOSE To evaluate the preclinical pharmacokinetics, antitumor efficacy, and mechanism of action of a novel orally active… (More)
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2005
2005
Ras mutation has been detected in approximately 20-30% of all human carcinomas, primarily in pancreatic, colorectal, lung and… (More)
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2005
2005
PURPOSE Treatment of hepatocellular carcinoma raised on cirrhotic liver represents a major endeavor because surgery and… (More)
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