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ABI-274

National Institutes of Health

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Broader (1)

Imidazoles

Papers overview

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2015
2015
Abstract B19: Discovery of novel tubulin inhibitor ABI-274 whose synergistic combination with vemurafenib overcome acquired vemurafenib resistance in BRAF mutated melanoma
Acquired clinical resistance to BRAF inhibitors such as vemurafenib or dabrafefnib arises frequently after short term of these… 
2011
2011
Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability
Microtubules are critical components of the cytoskeleton. Perturbing their function arrests the growth of a broad spectrum of… 
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