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ABCD2 gene

Known as: ALDRP, ADRENOLEUKODYSTROPHY-LIKE 1, ALDL1 
National Institutes of Health

Papers overview

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Review
2015
Review
2015
ABCD2 score and secondary stroke prevention
Objective: Patients with TIA have high risk of recurrent stroke and require rapid assessment and treatment. The ABCD2 clinical… 
2011
2011
Carotid stenosis as predictor of stroke after transient ischemic attacks
Highly Cited
2009
Highly Cited
2009
A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis.
Peroxisomes are essential organelles exerting key functions in fatty acid metabolism such as the degradation of very long-chain… 
Highly Cited
2009
Highly Cited
2009
ABCD2 Scores and Prediction of Noncerebrovascular Diagnoses in an Outpatient Population: A Case–Control Study
Background and Purpose— Among patients with transient ischemic attack, the ABCD2 score predicts short-term stroke risk. Use of… 
Review
2009
Review
2009
Early Diffusion Weighted MRI as a Negative Predictor for Disabling Stroke After ABCD2 Score Risk Categorization in Transient Ischemic Attack Patients
Background and Purpose— The prognostic value early diffusion-weighted magnetic resonance imaging (DWMRI) adds in the setting of… 
2008
2008
Distinct modulatory roles for thyroid hormone receptors TRalpha and TRbeta in SREBP1-activated ABCD2 expression.
Highly Cited
2005
Highly Cited
2005
Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage.
ATP-binding cassette (ABC) transporters facilitate unidirectional translocation of chemically diverse substances, ranging from… 
2003
2003
Thyroid hormone induction of the adrenoleukodystrophy-related gene (ABCD2).
X-linked adrenoleukodystrophy (X-ALD) is a demyelinating disorder associated with impaired very-long-chain fatty-acid (VLCFA… 
Highly Cited
2002
Highly Cited
2002
Cholesterol regulates ABCD2 expression: implications for the therapy of X-linked adrenoleukodystrophy.
X-linked adrenoleukodystrophy (X-ALD) is a severe neurodegenerative disorder with impaired very long-chain fatty acid (VLCFA… 
Highly Cited
2000
Highly Cited
2000
Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p.
Four ABC half transporters (ALDP, ALDRP, PMP70, and PMP69) have been identified in the mammalian peroxisomal membrane but no… 
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