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AAK1 gene

Known as: DKFZp686K16132, ADAPTOR PROTEIN 2-ASSOCIATED KINASE 1, AAK1 
 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Summary The highly diverse Numb-associated kinase (NAK) family has been linked to broad cellular functions including receptor… Expand
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Highly Cited
2016
Highly Cited
2016
The macroautophagy machinery has been implicated in MHC class II restricted antigen presentation. Here, we report that this… Expand
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Highly Cited
2015
Highly Cited
2015
ABSTRACT Hepatitis C virus (HCV) enters its target cell via clathrin-mediated endocytosis. AP-2-associated protein kinase 1 (AAK1… Expand
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Highly Cited
2012
Highly Cited
2012
Dendrite arborization and synapse formation are essential for wiring the neural circuitry. The evolutionarily conserved NDR1/2… Expand
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Highly Cited
2012
Highly Cited
2012
Novel therapies are urgently needed against hepatitis C virus infection (HCV), a major global health problem. The current model… Expand
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2007
2007
Phosphorylation is a critical step in regulating receptor transport through the endocytic pathway. AAK1 is a serine/threonine… Expand
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Highly Cited
2004
Highly Cited
2004
Phosphoinositides play a fundamental role in clathrin-coat assembly at the cell surface. Several endocytic components and… Expand
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Highly Cited
2003
Highly Cited
2003
AP-2 complexes are key components in clathrin-mediated endocytosis (CME). They trigger clathrin assembly, interact directly with… Expand
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Highly Cited
2002
Highly Cited
2002
During receptor-mediated endocytosis, AP2 complexes act as a bridge between the cargo membrane proteins and the clathrin coat by… Expand
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Highly Cited
2002
Highly Cited
2002
The μ2 subunit of the AP2 complex is known to be phosphorylated in vitro by a copurifying kinase, and it has been demonstrated… Expand
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