AAK1 gene

Known as: DKFZp686K16132, ADAPTOR PROTEIN 2-ASSOCIATED KINASE 1, AAK1 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2017
02420022017

Papers overview

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2012
2012
Dendrite arborization and synapse formation are essential for wiring the neural circuitry. The evolutionarily conserved NDR1/2… (More)
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2011
2011
The Notch pathway is involved in cell-cell signaling during development and adulthood from invertebrates to higher eukaryotes… (More)
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2008
2008
Here we investigate the role of rab5 and its cognate exchange factors rabex-5 and hRME-6 in the regulation of AP2 uncoating from… (More)
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2008
2008
Numb is an endocytic protein that is proposed to influence clathrin-coated pit assembly, although its mode of action and the… (More)
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2007
2007
Phosphorylation is a critical step in regulating receptor transport through the endocytic pathway. AAK1 is a serine/threonine… (More)
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2003
2003
AAK1, the adaptor-associated kinase 1, phosphorylates the micro2 subunit of AP2 and regulates the recruitment of AP2 to tyrosine… (More)
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Highly Cited
2003
Highly Cited
2003
AP-2 complexes are key components in clathrin-mediated endocytosis (CME). They trigger clathrin assembly, interact directly with… (More)
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Highly Cited
2002
Highly Cited
2002
The mu 2 subunit of the AP2 complex is known to be phosphorylated in vitro by a copurifying kinase, and it has been demonstrated… (More)
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2002
2002
During receptor-mediated endocytosis, AP2 complexes act as a bridge between the cargo membrane proteins and the clathrin coat by… (More)
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2002
2002
uring receptor-mediated endocytosis, AP2 complexes act as a bridge between the cargo membrane proteins and the clathrin coat by… (More)
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