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AAK1 gene

Known as: DKFZp686K16132, ADAPTOR PROTEIN 2-ASSOCIATED KINASE 1, AAK1 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
ABSTRACT Hepatitis C virus (HCV) enters its target cell via clathrin-mediated endocytosis. AP-2-associated protein kinase 1 (AAK1… 
Highly Cited
2012
Highly Cited
2012
Novel therapies are urgently needed against hepatitis C virus infection (HCV), a major global health problem. The current model… 
2007
2007
Phosphorylation is a critical step in regulating receptor transport through the endocytic pathway. AAK1 is a serine/threonine… 
Highly Cited
2004
Highly Cited
2004
Phosphoinositides play a fundamental role in clathrin-coat assembly at the cell surface. Several endocytic components and… 
Highly Cited
2003
Highly Cited
2003
AP-2 complexes are key components in clathrin-mediated endocytosis (CME). They trigger clathrin assembly, interact directly with… 
Highly Cited
2002
Highly Cited
2002
The μ2 subunit of the AP2 complex is known to be phosphorylated in vitro by a copurifying kinase, and it has been demonstrated… 
Highly Cited
2002
Highly Cited
2002
During receptor-mediated endocytosis, AP2 complexes act as a bridge between the cargo membrane proteins and the clathrin coat by…