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AA005

Known as: AA 005 
 
National Institutes of Health

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2 relations

Broader (2)

Fatty AlcoholsLactones

Papers overview

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2018
2018
Annonaceous acetogenin mimic AA005 suppresses human colon cancer cell growth in vivo through downregulation of Mcl-1
Annonaceous acetogenins are a well-established family of natural products with significant bioactivities, especially high… Expand
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2015
2015
Annonaceous acetogenin mimic AA005 induces cancer cell death via apoptosis inducing factor through a caspase-3-independent mechanism
BackgroundAnnonaceous acetogenins are a family of natural products with antitumor activities. Annonaceous acetogenin mimic AA005… Expand
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2014
2014
Identification of novel bivalent mimetics of annonaceous acetogenins via a scaffold-hopping strategy.
A series of novel bivalent mimetics of annonaceous acetogenins have been designed, synthesized, and evaluated. Among these… Expand
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2012
2012
Identification of an Annonaceous Acetogenin Mimetic, AA005, as an AMPK Activator and Autophagy Inducer in Colon Cancer Cells
Annonaceous acetogenins, a large family of naturally occurring polyketides isolated from various species of the plant genus… Expand
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2011
2011
Potent antitumor mimetics of annonaceous acetogenins embedded with an aromatic moiety in the left hydrocarbon chain part.
Annonaceous acetogenins are a large family of naturally occurring polyketides exhibiting remarkable anticancer activities. The… Expand
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2008
2008
Tuning the acyclic ether moiety of anticancer agent AA005 with conformationally constrained fragments.
A new series of anticancer annonaceous acetogenin mimetics were designed, synthesized, and evaluated based on our previously… Expand
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2008
2008
Tuning the Acyclic Ether Moiety of Anticancer Agent AA005 with Conformationally Constrained Fragments
A new series of anticancer annonaceous acetogenin mimetics were designed, synthesized, and evaluated based on our previously… Expand
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2007
2007
Annonaceous acetogenin mimics bearing a terminal lactam and their cytotoxicity against cancer cells.
Annonaceous acetogenins are a large class of naturally occurring polyketides exhibiting potent anticancer activities. Based on… Expand
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2005
2005
Synthesis of a tetra-deuterium-labeled derivative of potent and selective anticancer agent AA005
Annonaceous acetogenins are a series of potent naturally occurring anticancer agents, which act as inhibitors of complex I in… Expand
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2003
2003
Induction of Cell Death of Gastric Cancer Cells by a Modified Compound of the Annonaceous Acetogenin Family
Annonaceous acetogenins are a family of natural products with antitumor activities. The polyether mimic AA005 has been… Expand
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