A498

An adenocarcinoma cell line established from a 52 year old female patient with renal cell carcinoma.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Renal cell carcinoma (RCC) is a malignancy with a poor prognosis. We aimed to explore whether the expression of Long… (More)
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Highly Cited
2010
Highly Cited
2010
The mammalian target of rapamycin (mTOR) is a major component of the phosphoinositide 3-kinase (PI3K)/AKT signaling pathway that… (More)
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Highly Cited
2009
Highly Cited
2009
BTG3/ANA/APRO4 has been reported to be a tumor suppressor gene in some malignancies. It constitutes important negative regulatory… (More)
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Highly Cited
2004
Highly Cited
2004
Clinically, there is a great need for small molecule inhibitors that could control pathogenic effects of transforming growth… (More)
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Highly Cited
2003
Highly Cited
2003
Organ-specific metastasis is governed, in part, by interactions between chemokine receptors on cancer cells and matching… (More)
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2003
2003
Previously, we showed that arsenic trioxide potently inhibited the growth of myeloma cells and head and neck cancer cells. Here… (More)
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Highly Cited
2002
Highly Cited
2002
Transforming growth factor beta1 (TGF-beta1) is a potent fibrotic factor responsible for the synthesis of extracellular matrix… (More)
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Highly Cited
2001
Highly Cited
2001
Lipid rafts are sphingolipid- and cholesterol-rich membrane microdomains that are insoluble in nonionic detergents, have a low… (More)
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1997
1997
Experiments performed on a cell line (A498) derived from a human kidney carcinoma revealed non-centrosomal microtubules in the… (More)
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Highly Cited
1987
Highly Cited
1987
The development of a cell culture system that produces erythropoietin (Epo) in a regulated manner has been the focus of much… (More)
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