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A-804598

 
National Institutes of Health

Papers overview

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2019
2019
Background: P2X7 receptors (P2X7R) are ligand-gated ion channels activated by adenosine 5’-triphosphate (ATP), which are involved… Expand
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2017
2017
BackgroundATP-gated P2X7 is a non-selective cation channel, which participates in a wide range of cellular functions as well as… Expand
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2017
2017
Autophagy and inflammation play determinant roles in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS), an adult-onset… Expand
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2017
2017
BackgroundThe P2X7 receptor has been shown to play a fundamental role in the initiation and sustenance of the inflammatory… Expand
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2017
2017
Psoriasis is a chronic inflammatory skin disorder, characterised by epidermal hyperplasia (acanthosis) and leukocyte infiltration… Expand
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2017
2017
Chronic pain is supported by sterile inflammation that induces sensitisation of sensory neurons to ambient stimuli including… Expand
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2015
2015
The ATP-gated ion channel P2X7 has emerged as a potential central nervous system (CNS) drug target based on the hypotheses that… Expand
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2014
2014
Stress leads to neuroinflammatory and behavioral consequences through upregulation of inflammatory-related cytokines within the… Expand
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2009
2009
ATP-sensitive P2X7 receptors are localized on cells of immunological origin including peripheral macrophages and glial cells in… Expand
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