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A 79175

Known as: A-79175, Abbott 79175, Abbott-79175 
National Institutes of Health

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A 78773

Papers overview

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2013
2013
Local inhibition of 5-lipoxygenase enhances bone formation in a rat model
Objectives Recent studies have shown that modulating inflammation-related lipid signalling after a bone fracture can accelerate… 
Highly Cited
1998
Highly Cited
1998
Inhibitors of lipoxygenase: a new class of cancer chemopreventive agents.
5-Lipoxygenase is a key enzyme in the metabolism of arachidonic acid to leukotrienes. The preventive efficacy of 5-lipoxygenase… 
1998
1998
The role of platelet-activating factor (PAF) and the efficacy of ABT-491, a highly potent and selective PAF antagonist, in experimental allergic rhinitis.
Platelet-activating factor (PAF) may be an important mediator of allergic rhinitis. In the present study we evaluated the… 
1998
1998
Aqueous Stability of SB 210661: Kinetics and Primary Degradation Mechanisms of an N‐Hydroxyurea‐containing 5‐Lipoxygenase Inhibitor
SB 210661, (S)‐N‐hydroxy‐N‐[2,3‐dihydro‐6‐(2,6‐difluorophenylmethoxy)‐3‐benzofuranyl]urea, is a potent and selective inhibitor of… 
1996
1996
Polymorphism and crystallization behavior of Abbott-79175, a second-generation 5-lipoxygenase inhibitor.
The crystal polymorphism of Abbott-79175, a potent second-generation 5-lipoxygenase inhibitor, has been studied. Crystallization… 
1995
1995
Optimization of the potency and duration of action of N-hydroxyurea 5-lipoxygenase inhibitors.
As in vitro glucuronidation assay and several biochemical assays were utilized to discover potent new N-hydroxyurea-containing 5… 
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