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A 769662

Known as: A-769662 
National Institutes of Health

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2 relations

Broader (2)

PyronesThiophenes

Papers overview

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2017
2017
The AMP-Dependent Protein Kinase (AMPK) Activator A-769662 Causes Arterial Relaxation by Reducing Cytosolic Free Calcium Independently of an Increase in AMPK Phosphorylation
Although recent studies reveal that activation of the metabolic and Ca2+ sensor AMPK strongly inhibits smooth muscle contraction… 
Highly Cited
2016
Highly Cited
2016
Activating AMP-activated protein kinase by an α1 selective activator compound 13 attenuates dexamethasone-induced osteoblast cell death.
2016
2016
Preconditioning mice with activators of AMPK ameliorates ischemic acute kidney injury in vivo.
This study had two objectives: 1) to determine whether preconditioning cultured proximal tubular cells (PTCs) with… 
2016
2016
Cilostazol Suppresses IL-23 Production in Human Dendritic Cells via an AMPK-Dependent Pathway
Background/Aims: Cilostazol has been previously demonstrated to inhibit IL-23 production in human synovial macrophages via a RhoA… 
2015
2015
Bavachalcone-Induced Manganese Superoxide Dismutase Expression through the AMP-Activated Protein Kinase Pathway in Human Endothelial Cells
Mitochondrial oxidative stress has been suggested as a major etiological factor in cardiovascular diseases. Manganese superoxide… 
2015
2015
AMP-Activated Protein Kinase Regulates the Cell Surface Proteome and Integrin Membrane Traffic
The cell surface proteome controls numerous cellular functions including cell migration and adhesion, intercellular communication… 
2015
2015
Duodenal energy sensing regulates hepatic glucose output
The maintenance of blood glucose involves the coordination of multiple organ systems. Two new studies indicate that metformin and… 
2014
2014
Alpha1 catalytic subunit of AMPK modulates contractile function of cardiomyocytes through phosphorylation of troponin I.
2014
2014
AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer
Depletion of cellular energy activates the AMP-activated kinase (AMPK) to favor energy-producing catabolic processes during… 
2010
2010
Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species
Abstract Globular adiponectin (gAd) induces the generation of reactive oxygen species (ROS) and nitric oxide (NO) in the murine… 
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