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A 4166

Known as: A-4166 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

nateglinide

Papers overview

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2001
2001
Randomized dose ranging study of the reduction of fasting and postprandial glucose in type 2 diabetes by nateglinide (A-4166).
OBJECTIVE This randomized crossover double-blind placebo-controlled study aimed to assess the efficacy of nateglinide (A-4166), a… 
Highly Cited
2000
Highly Cited
2000
Pancreatic beta-cell K(ATP) channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide.
Nateglinide (A-4166) is an amino acid derivative with insulinotrophic action in clinical development for treatment of type 2… 
Highly Cited
1999
Highly Cited
1999
The Effect of Food on the Oral Bioavailability and the Pharmacodynamic Actions of the Insulinotropic Agent Nateglinide in Healthy Subjects
Nateglinide (Starlix®, SDZ DJN 608 or A‐4166), a new insulinotropic agent, is intended to be administered prior to a meal in… 
Highly Cited
1997
Highly Cited
1997
Hypoglycaemic and insulinotropic effects of a novel oral antidiabetic agent, (−)‐N‐(trans‐4‐isopropylcyclohexane‐carbonyl)‐d‐phenylalanine (A‐4166)
(−)‐N‐(trans‐4‐isopropylcyclohexanecarbonyl)‐d‐phenylalanine (A‐4166), a novel oral hypoglycaemic agent is a non‐sulphonylurea… 
1997
1997
Effect of a new hypoglycemic agent, A-4166 [(-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine], on postprandial blood glucose excursion: comparison with voglibose and glibenclamide.
(-)-N-(trans-4-Isopropylcyclohexanecarbonyl)-D-phenylalanine (A-4166) is a new nonsulfonylurea hypoglycemic agent that lowers… 
1997
1997
Dynamics of the cationic and secretory responses to A‐4166 in perifused pancreatic islets
Summary— The dynamics of the cationic and secretory response to A‐4166, a hypoglycemic meglitinide analogue, was investigated in… 
Highly Cited
1995
Highly Cited
1995
A new hypoglycemic agent, A-4166, inhibits ATP-sensitive potassium channels in rat pancreatic beta-cells.
Effects of a new hypoglycemic drug, N-[trans-4-isopropylcyclohexy-carbonyl]-D-phenylalanine (A-4166), on membrane current were… 
1995
1995
Conformational analysis of non-sulfonylurea hypoglycemic agents of the meglitinide family.
1995
1995
Insulinotropic action of meglitinide analogues: modulation by an activator of ATP-sensitive K+ channels and high extracellular K+ concentrations.
Review
1995
Review
1995
Stimulation of Insulin Release by Non-Sulfonylurea Hypoglycemic Agents: The Meglitinide Family
  • W. Malaisse
  • Hormone and metabolic research = Hormon- und…
  • 1995
  • Corpus ID: 21156262
Several new non-sulfonylurea hypoglycemic agents such as A-4166, KAD-1229 and repaglinide are structurally related to meglitinide… 
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