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A-1210477

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
To evaluate BCL‐2 family signaling molecules in head and neck squamous cell carcinoma (HNSCC) and examine the ability of… Expand
2019
2019
First-generation bromodomain extra-terminal protein (BETP) inhibitors (BETi) (e.g., OTX015) that disrupt binding of BETP BRD4 to… Expand
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2018
2018
ObjectiveThere are number of studies which report that BCL-2 anti-apoptotic proteins (e.g. BCL-2, BCL-XL, and MCL-1) are highly… Expand
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Highly Cited
2017
Highly Cited
2017
Acute myeloid leukemia (AML) is a serious disease. The 5-year survival rates remain frustratingly low (65% for children and 26… Expand
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2017
2017
The concept of using BH3 mimetics as anticancer agents has been substantiated by the efficacy of selective drugs, such as… Expand
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2016
2016
As a population, non-Hodgkin’s lymphoma (NHL) cell lines positive for the t(14;18) translocation and/or possessing elevated BCL2… Expand
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Highly Cited
2015
Highly Cited
2015
The anti-apoptotic protein MCL-1 is a key regulator of cancer cell survival and a known resistance factor for small-molecule BCL… Expand
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Highly Cited
2015
Highly Cited
2015
Hyperexpression of antiapoptotic BCL-2 family proteins allows cells to survive despite the receipt of signals that would… Expand
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2015
2015
First MCL-1-selective BH3 mimetics as potential therapeutics for targeted treatment of cancer 
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2015
2015
As a population, non-Hodgkin's lymphoma (NHL) cell lines positive for the t(14;18) translocation and/or possessing elevated BCL2… Expand
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