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A-1210477

National Institutes of Health

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2 relations

Broader (2)

IndolesSulfonamides

Papers overview

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2020
2020
Albendazole-Induced SIRT3 Upregulation Protects Human Leukemia K562 Cells from the Cytotoxicity of MCL1 Suppression
Previous studies have shown that MCL1 stabilization confers cancer cells resistance to microtubule targeting agents (MTAs) and… 
2015
2015
Mechanisms of Acquired Resistance to Venetoclax in Preclinical AML Models
BH3-mimetic ABT-199 (venetoclax, VEN) is a selective small-molecule antagonist of the anti-apoptotic BCL-2 protein. It binds to… 
Review
2014
Review
2014
CDK9 Inhibition Reverses Resistance to ABT-199 (GDC-0199) By Down-Regulating MCL-1
All authors are employees of AbbVie and participated in the design, conduct, and interpretation of these studies. AbbVie and… 
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