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9-aminophenanthrene

 
National Institutes of Health

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Phenanthrenes

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Highly Cited
2015
Highly Cited
2015
Nitrogen-embedded buckybowl and its assembly with C60
Curved π-conjugated molecules have attracted considerable interest because of the unique properties originating from their curved… Expand
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2007
2007
Dissecting the thermodynamics and cooperativity of ligand binding in cytochrome P450eryF.
Conformational flexibility and cooperativity in ligand recognition are two key aspects of the catalytic diversity of cytochrome… Expand
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2006
2006
NMR studies of ligand binding to P450(eryF) provides insight into the mechanism of cooperativity.
Cytochrome P450's (P450's) catalyze the oxidative metabolism of most drugs and toxins. Although extensive studies have proven… Expand
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Review
2004
Review
2004
“Allosterism” in the Elementary Steps of the Cytochrome P450 Reaction Cycle
Cytochrome P450‐dependent drug metabolism in vitro frequently deviates from simple Michaelis‐Menten kinetic models, and… Expand
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2003
2003
Homotropic versus heterotopic cooperativity of cytochrome P450eryF: a substrate oxidation and spectral titration study.
P450eryF is the only bacterial P450 to show cooperativity of substrate binding and oxidation. However, the studies reported so… Expand
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2002
2002
Site-directed mutagenesis of cytochrome P450eryF: implications for substrate oxidation, cooperativity, and topology of the active site.
The role of five active-site residues (Phe-78, Gly-91, Ser-171, Ile-174, and Leu-175) has been investigated in P450eryF, the only… Expand
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2001
2001
Copper(II)-mediated oxidative coupling of 2-aminonaphthalene homologues. Competition between the straight dimerization and the formation of carbazoles.
Whereas the Cu(II)-mediated oxidative coupling of 2-aminonaphthalenes 7a and 7b results in the clean formation of 1,1… Expand
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2000
2000
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity.
Several mammalian cytochrome P450 (P450) isoforms demonstrate homotropic cooperativity with a number of substrates, including… Expand
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1998
1998
HPLC on Chiralcel OJ-R for enantiomer separation and analysis of ketoprofen, from horse plasma, as the 9-aminophenanthrene derivative.
Racemic ketoprofen is a non-steroidal anti-inflammatory drug used to treat musculoskeletal and colic conditions in horses. The… Expand
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1993
1993
Interaction of hepatic microsomal epoxide hydrolase derived from a recombinant baculovirus expression system with an azarene oxide and an aziridine substrate analogue.
A recombinant baculovirus (vEHX) encoding rat hepatic microsomal epoxide hydrolase has been constructed. Infection of Spodoptera… Expand
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