9-aminophenanthrene
National Institutes of Health
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Conformational flexibility and cooperativity in ligand recognition are two key aspects of the catalytic diversity of cytochrome…
We here report the synthesis of 10-aryl-9-hydroxy- and 10-aryl-9-aminophenanthrenes by reaction of the anions of 9-phenanthrol…
Cytochrome P450‐dependent drug metabolism in vitro frequently deviates from simple Michaelis‐Menten kinetic models, and…
The excited singlet states of 9-aminophenanthrene and its N-aminoalkyl derivatives are strongly fluorescent in cyclohexane…
The role of five active-site residues (Phe-78, Gly-91, Ser-171, Ile-174, and Leu-175) has been investigated in P450eryF, the only…
Racemic ketoprofen is a non‐steroidal anti‐inflammatory drug used to treat musculoskeletal and colic conditions in horses. The…
A recombinant baculovirus (vEHX) encoding rat hepatic microsomal epoxide hydrolase has been constructed. Infection of Spodoptera…
The effects of lithocholic acid on the mutagenicity of 24 aromatic amines in the Ames assay were examined. When lithocholic acid…