9-aminophenanthrene
National Institutes of Health
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Curved π-conjugated molecules have attracted considerable interest because of the unique properties originating from their curved…
Conformational flexibility and cooperativity in ligand recognition are two key aspects of the catalytic diversity of cytochrome…
Cytochrome P450's (P450's) catalyze the oxidative metabolism of most drugs and toxins. Although extensive studies have proven…
We here report the synthesis of 10-aryl-9-hydroxy- and 10-aryl-9-aminophenanthrenes by reaction of the anions of 9-phenanthrol…
Cytochrome P450‐dependent drug metabolism in vitro frequently deviates from simple Michaelis‐Menten kinetic models, and…
The excited singlet states of 9-aminophenanthrene and its N-aminoalkyl derivatives are strongly fluorescent in cyclohexane…
Whereas the Cu(II)-mediated oxidative coupling of 2-aminonaphthalenes 7a and 7b results in the clean formation of 1,1…
Several mammalian cytochrome P450 (P450) isoforms demonstrate homotropic cooperativity with a number of substrates, including…
Racemic ketoprofen is a non‐steroidal anti‐inflammatory drug used to treat musculoskeletal and colic conditions in horses. The…
A recombinant baculovirus (vEHX) encoding rat hepatic microsomal epoxide hydrolase has been constructed. Infection of Spodoptera…