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9-aminoacridine-4-carboxamide
Known as:
9-AA-4-CA
National Institutes of Health
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1 relation
Broader (1)
Aminoacridines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Non-covalent duplex to duplex crosslinking of DNA in solution revealed by single molecule force spectroscopy.
B. Rackham
,
L. Howell
,
A. Round
,
M. Searcey
Organic and biomolecular chemistry
2013
Corpus ID: 36667196
Small molecules that interact with DNA, disrupting the binding of transcription factors or crosslinking DNA into larger…
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2002
2002
The interaction of DNA-targeted 9-aminoacridine-4-carboxamide platinum complexes with DNA in intact human cells.
M. D. Temple
,
P. Recabarren
,
W. Mcfadyen
,
R. J. Holmes
,
W. Denny
,
V. Murray
Biochimica et Biophysica Acta
2002
Corpus ID: 25037524
2001
2001
cis-Dichloroplatinum(II) complexes tethered to 9-aminoacridine-4-carboxamides: synthesis and action in resistant cell lines in vitro.
R. J. Holmes
,
M. McKeage
,
V. Murray
,
W. Denny
,
W. Mcfadyen
Journal of Inorganic Biochemistry
2001
Corpus ID: 20126982
2000
2000
Acridinecarboxamide topoisomerase poisons: structural and kinetic studies of the DNA complexes of 5-substituted 9-amino-(N-(2-dimethylamino)ethyl)acridine-4-carboxamides.
A. Adams
,
J. Guss
,
C. Collyer
,
W. Denny
,
A. S. Prakash
,
L. P. Wakelin
Molecular Pharmacology
2000
Corpus ID: 9347557
For a series of antitumor-active 5-substituted 9-aminoacridine-4-carboxamide topoisomerase II poisons, we have used X-ray…
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1992
1992
Sequence specificity of the binding of 9-aminoacridine- and amsacrine-4-carboxamides to DNA studied by DNase I footprinting.
C. Bailly
,
W. Denny
,
L. Mellor
,
L. P. Wakelin
,
M. Waring
Biochemistry
1992
Corpus ID: 10460912
DNase I footprinting has been used to probe the sequence selectivity of binding of a series of intercalating amsacrine-4…
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1991
1991
Synthesis and evaluation of DNA-targeted spatially separated bis(aniline mustards) as potential alkylating agents with enhanced DNA cross-linking capability.
T. A. Gourdie
,
A. S. Prakash
,
L. P. Wakelin
,
P. D. Woodgate
,
W. Denny
Journal of Medicinal Chemistry
1991
Corpus ID: 46057123
DNA-targeted separated bis-mustards were synthesized by attaching aniline mono-mustards at the 4- and 9-positions of the DNA…
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1988
1988
Energetics and stereochemistry of DNA complexation with the antitumor AT specific intercalators tilorone and m-AMSA.
K. Chen
,
N. Gresh
,
B. Pullman
Nucleic Acids Research
1988
Corpus ID: 17230202
Computations by the SIBFA method on the intercalative interaction energies of tilorone and m-AMSA with B-DNA representative…
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Highly Cited
1987
Highly Cited
1987
Relationships between DNA-binding kinetics and biological activity for the 9-aminoacridine-4-carboxamide class of antitumor agents.
L. P. Wakelin
,
G. Atwell
,
G. Rewcastle
,
W. Denny
Journal of Medicinal Chemistry
1987
Corpus ID: 23182798
The kinetics of dissociation of calf thymus DNA complexes of the new intercalating antitumor drug N-[2-(dimethylamino)ethyl]-9…
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1987
1987
Crystallographic and molecular mechanics calculations on the anti-tumor drugs N-[(2-dimethylamino)ethyl]-and N-[(2-dimethyl-amino)butyl]-9-aminoacridine-4-carboxamides and their dications…
B. Hudson
,
R. Kuroda
,
W. Denny
,
S. Neidle
Journal of Biomolecular Structure and Dynamics
1987
Corpus ID: 42791435
The molecular structures of the N-(2-dimethylamino)ethyl and N-(2-dimethylamino)butyl derivatives of 9-aminoacridine-4…
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1987
1987
Groove selectivity in the interaction of 9‐aminoacridine‐4‐carboxamide antitumor agents with DNA
K. Chen
,
N. Gresh
,
B. Pullman
FEBS Letters
1987
Corpus ID: 35812409
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