9-aminoacridine-4-carboxamide

Small molecules that interact with DNA, disrupting the binding of transcription factors or crosslinking DNA into larger… Expand

As part of an ongoing drug development programme, this paper describes the sequence specificity and time course of DNA adduct… Expand

A series of intercalator-tethered platinum(II) complexes PtLCl(2) have been prepared where L are the diamine ligands N-[2… Expand

For a series of antitumor-active 5-substituted 9-aminoacridine-4-carboxamide topoisomerase II poisons, we have used X-ray… Expand

DNase I footprinting has been used to probe the sequence selectivity of binding of a series of intercalating amsacrine-4… Expand

DNA-targeted separated bis-mustards were synthesized by attaching aniline mono-mustards at the 4- and 9-positions of the DNA… Expand

Computations by the SIBFA method on the intercalative interaction energies of tilorone and m-AMSA with B-DNA representative… Expand

The kinetics of dissociation of calf thymus DNA complexes of the new intercalating antitumor drug N-[2-(dimethylamino)ethyl]-9… Expand

Theoretical quantitative evaluation of the intercalative binding to DNA of the new antitumor drug 9-aminoacridine-4-carboxamide… Expand

The molecular structures of the N-(2-dimethylamino)ethyl and N-(2-dimethylamino)butyl derivatives of 9-aminoacridine-4… Expand