9,10-epoxy-12-octadecenoate

We have observed that neutrophils biosynthesize linoleate epoxide, 9,10-epoxy-12-octadecenoate, and have named it leukotoxin… Expand

The present study was carried out to explore the involvement of nitric oxide (NO) and superoxide anion (O2.-) in Leukotoxin (Lx… Expand

We examined the mechanism of leukotoxin, 9,10-epoxy-12-octadecenoate (Lx)-induced lung injury in blood-free, physiological salt… Expand

Leukotoxin (Lx), a cytochrome P-450-dependent metabolite of linoleate synthesized by neutrophils or synthesized by OH- and… Expand

To investigate how mitochondrial function was affected in leukotoxin (Lx)-,9,10-epoxy-12-octadecenoate-induced lung injury, lung… Expand

We previously demonstrated that neutrophils biosynthesize the Iinoleate epoxide, 9,10-epoxy-12-octadecenoate, from linoleate and… Expand

It is postulated that toxic substances (burn toxin) synthesized in burned skin are transferred into general circulation and cause… Expand

We demonstrated that linoleate epoxide (9,10-epoxy-12-octadecenoate) exists in human burned skin and in lung lavages in patients… Expand

Pulmonary influxed neutrophils have been suggested to be involved in the development of hyperoxia-induced lung injury. We… Expand

In lung lavages of rat after pure oxygen breathing, a toxic linoleate peroxide, 9,10-epoxy-12-octadecenoate, and its isomer, 12… Expand