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7-methoxytacrine

Known as: 9-amino-7-methoxy-1,2,3,4-tetrahydroacridine 
National Institutes of Health

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TA-03

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Tacrine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Development of 2-Methoxyhuprine as Novel Lead for Alzheimer’s Disease Therapy
Tacrine (THA), the first clinically effective acetylcholinesterase (AChE) inhibitor and the first approved drug for the treatment… 
2012
2012
Acetylcholinesterase inhibitors as pretreatment before acute exposure to organophosphates: assessment using methyl-paraoxon.
Prophylactic administration of reversible acetylcholinesterase (AChE) inhibitors can protect against the lethal effects of… 
2011
2011
Synthesis and in vitro evaluation of 7-methoxy-N-(pent-4-enyl)-1,2,3,4-tetrahydroacridin-9-amine-new tacrine derivate with cholinergic properties.
2010
2010
Synthesis and In Vitro Evaluation of N-(Bromobut-3-en-2-yl)-7-methoxy-1,2,3,4-tetrahydroacridin-9-amine as a Cholinesterase Inhibitor with Regard to Alzheimer's Disease Treatment
A new tacrine based cholinesterase inhibitor, N-(bromobut-3-en-2-yl)-7-methoxy-1,2,3,4-tetrahydroacridin-9-amine (1), was… 
2005
2005
Intestinal single-pass in situ perfusion technique in rat: the influence of L-carnitine on absorption of 7-methoxytacrine.
7-Methoxytacrine (7-MEOTA) is an acetylcholine-esterase inhibitor that is potentially useful in the therapy of some… 
1998
1998
Capillary zone electrophoretic determination of some drugs against Alzheimer's disease.
1991
1991
Negative Effects of Tacrine (Tetrahydroaminoacridine) and Methoxytacrine on the Metabolism of Acetylcholine in Brain Slices Incubated Under Conditions Stimulating Neurotransmitter Release
Abstract: The effects of tacrine (1,2,3,4‐tetrahydro‐9‐aminoacridine) and 7‐methoxytacrine on the metabolism of brain… 
1991
1991
Positive and Negative Effects of Tacrine (Tetrahydroaminoacridine) and Methoxytacrine on the Metabolism of Acetylcholine in Brain Cortical Prisms Incubated Under “Resting”Conditions
Abstract: The effects of tacrine (1,2,3,4‐tetrahydro‐9‐aminoacridine) and 7‐methoxytacrine on the metabolism of acetylcholine… 
1991
1991
Pharmacokinetics and tolerance of 7-methoxytacrine following the single dose administration in healthy volunteers.
7-methoxy-tetrahydroaminoacridine (7-MEOTA) is a new reversible cholinesterase inhibitor. Forty-eight young male volunteers… 
1979
1979
In vivo kinetics of blood cholinesterase inhibition by 9-amino-1, 2, 3, 4-tetrahydroacridine, its 7-methoxy derivative and physostigmine in rats.
In vivo inhibition of blood acetylcholinesterase activity by 9-amino-1, 2, 3, 4-tetrahydroacridine, its 7-methoxy derivative and… 
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