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7-Deaza-7-thia-8-oxoguanosine

Known as: 5-amino-3-ribofuranosylthiazolo(4,5-d)pyrimidine-2,7(3H,6H)-dione, 7-Thia-8-oxoguanosine 
National Institutes of Health

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isatoribine

Papers overview

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2000
2000
Modulatory effect of 7-thia-8-oxoguanosine on proliferation of rat thymocytes in vitro stimulated with concanavalin A.
1995
1995
Broad-spectrum activity of 8-chloro-7-deazaguanosine against RNA virus infections in mice and rats
1992
1992
Immunomodulatory activity of a novel nucleoside, 7-thia-8-oxoguanosine: I. Activation of natural killer cells in mice.
We reported recently that a novel immunomodulator, 7-thia-8-oxoguanosine (7T8OG)2 inhibited formation of pulmonary melanoma… 
1991
1991
Immunoenhancing properties and antiviral activity of 7-deazaguanosine in mice
The nucleotide analog 7-deazaguanosine has not previously been reported to possess biological (antiviral or antitumor) properties… 
1990
1990
Roles of interferon and natural killer cells in the antiviral activity of 7-thia-8-oxoguanosine against Semliki Forest virus infections in mice.
1990
1990
Antiviral activity of the novel immune modulator 7-thia-8-oxoguanosine.
A novel thiazolopyrimidine nucleoside, 5-amino-3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidine-2,7(3H,6H) -dione (7-thia-8… 
1990
1990
Guanosine analogues. Synthesis of nucleosides of certain 3-substituted 6-aminopyrazolo[3,4-d]pyrimidin-4(5H)-ones as potential immunotherapeutic agents.
Several guanosine analogues were synthesized in the pyrazolo[3,4-d]pyrimidine ring system with various substituents at the 3… 
1990
1990
Activation of the respiratory burst in murine phagocytes by certain guanine ribonucleosides modified at the 7 and 8 positions: possible involvement of a pertussis toxin-sensitive G-protein.
1990
1990
A novel guanosine analog, 7-thia-8-oxoguanosine, enhances macrophage and lymphocyte antibody-dependent cell-mediated cytotoxicity.
Highly Cited
1989
Highly Cited
1989
Broad-spectrum in vivo antiviral activity of 7-thia-8-oxoguanosine, a novel immunopotentiating agent
A novel immunopotentiating agent, 5-amino-3-beta-D-ribofuranosylthiazolo [4,5-d]pyrimidine-2,7(3H,6H)-dione (7-thia-8… 
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