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6-bromoindirubin-3'-oxime

Known as: 6BIO cpd 
National Institutes of Health

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2 relations

Broader (2)

IndolesOximes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Activation of Wnt/β-Catenin Signaling Pathway Enhances the Derivation of Buffalo (Bubalus bubalis) Embryonic Stem Cell-Like Cells.
Wnt/β-Catenin signaling pathway plays an important role in maintaining self-renewal and pluripotency of human and mouse embryonic… 
2017
2017
The Indirubin Derivative 6-Bromoindirubin-3′-Oxime Activates Proteostatic Modules, Reprograms Cellular Bioenergetic Pathways, and Exerts Antiaging Effects
Abstract Aims: Organismal aging can be delayed by mutations that either activate stress responses or reduce the nutrient-sensing… 
2014
2014
Mathematical Model of a Telomerase Transcriptional Regulatory Network Developed by Cell-Based Screening: Analysis of Inhibitor Effects and Telomerase Expression Mechanisms
Cancer cells depend on transcription of telomerase reverse transcriptase (TERT). Many transcription factors affect TERT, though… 
2013
2013
Hela Cells Consist of Two Cell Types, as Evidenced by Cytochemical Staining for Alkaline Phosphatase Activity: A Possible Model for Cancer Stem Cell Study
Alkaline phosphatase (ALP) is known to be expressed in the several somatic stem cells and cancer cells. To investigate whether… 
2013
2013
Αντικαρκινική δράση των συνθετικών αναλόγων ιντιρουπίνης 6-bromoindirubin-3'-oxime και 7-bromoindirubin-3'-oxime σε καρκινικά κύτταρα μαστού, προστάτη και οστεοσαρκώματος
2012
2012
Effect of GSK-3 inhibitor on the proliferation of multipotent male germ line stem cells (mGSCs) derived from goat testis.
2012
2012
Effect of 6-bromoindirubin-3'-oxime on human deciduous tooth dental pulp cells
Stem cells have been a recent focus of regenerative medicine research. They originate from various tissues including human dental… 
2012
2012
Enhanced Wnt/β‐catenin signalling during tooth morphogenesis impedes cell differentiation and leads to alterations in the structure and mineralisation of the adult tooth
Previous studies have indicated that over‐activation of the wingless interaction site (Wnt)/β‐catenin signalling pathway has… 
2012
2012
Glycogen synthase kinase 3 (GSK3) inhibitor 6-bromoindirubin-3'-oxime (BIO) promotes the proliferation of mouse male germline stem cells (mGSCs) under serum- and feeder-free conditions
The 6-bromoindirubin-3'-oxime (BIO), as one of glycogen synthase kinase 3 (GSK3) inhibitors, is a key regulator of many signaling… 
2010
2010
Genome-wide gene expression profiling reveals aberrant MAPK and Wnt signaling pathways associated with early parthenogenesis.
Mammalian parthenogenesis could not survive but aborted during mid-gestation, presumably because of lack of paternal gene… 
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