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6,8-dimethylpterin

National Institutes of Health

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Pterins

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1995
1995
pH dependence of enzyme reaction rates and deuterium isotope effects on the reduction of a new mechanism-based substrate by dihydrofolate reductase DHFR.
The enzyme kinetics of the reduction of the substrate 6,8-dimethylpterin by chicken and recombinant human dihydrofolate… 
1993
1993
Novel mechanism‐based substrates of dihydrofolate reductase and the thermodynamics of ligand binding: A comparison of theory and experiment for 8‐methylpterin and 6,8‐dimethylpterin
Molecular dynamics simulation and free energy perturbation techniques have been used to study the relative binding free energies… 
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