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5P12-RANTES

National Institutes of Health

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Broader (1)

beta-Chemokines

Papers overview

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Review
2019
Review
2019
Development and pharmacokinetics of a combination vaginal ring for sustained release of dapivirine and the protein microbicide 5P12-RANTES.
2019
2019
Sustained release silk fibroin discs: Antibody and protein delivery for HIV prevention
2017
2017
Pharmacokinetics of the Protein Microbicide 5P12-RANTES in Sheep following Single-Dose Vaginal Gel Administration
ABSTRACT 5P12-RANTES, a chemokine analogue that potently blocks the HIV CCR5 coreceptor, is being developed as both a vaginal and… 
2017
2017
The Effect of N-Terminal Cyclization on the Function of the HIV Entry Inhibitor 5P12-RANTES
Despite effective treatment for those living with Human Immunodeficiency Virus (HIV), there are still two million new infections… 
2017
2017
Resistance to the CCR 5 inhibitor 5 P 12-RANTES requires a difficult evolution from CCR 5 to CXCR 4 coreceptor use
Viral resistance to small molecule allosteric inhibitors of CCR5 is well documented, and involves either selection of preexisting… 
2017
2017
Stability of 5P12-RANTES, A Candidate Rectal Microbicide, in Human Rectal Lavage.
In the absence of an effective vaccine, strategies to prevent HIV transmission are urgently needed. Condomless receptive anal… 
2016
2016
A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris
2013
2013
Using glycosaminoglycan/chemokine interactions for the long-term delivery of 5P12-RANTES in HIV prevention.
5P12-RANTES is a recently developed chemokine analogue that has shown high level protection from SHIV infection in macaques… 
2011
2011
Resistance to the CCR5 Inhibitor 5P12-RANTES Requires a Difficult Evolution from CCR5 to CXCR4 Coreceptor Use
Viral resistance to small molecule allosteric inhibitors of CCR5 is well documented, and involves either selection of preexisting… 
Highly Cited
2008
Highly Cited
2008
Highly potent, fully recombinant anti-HIV chemokines: Reengineering a low-cost microbicide
New prevention strategies for use in developing countries are urgently needed to curb the worldwide HIV/AIDS epidemic. The N… 
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