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5F-203

National Institutes of Health

Papers overview

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Review
2012
Review
2012
Cytochrome P450 1A1-mediated anticancer drug discovery: in silico findings
Introduction: Target-specific drugs may offer fewer side/adverse effects in comparison with other anticancer agents and thus save… 
2011
2011
Preclinical Development CYP 2 S 1 and CYP 2 W 1 Mediate 2-( 3 , 4-Dimethoxyphenyl )-5-Fluorobenzothiazole ( GW-610 , NSC 721648 ) Sensitivity in Breast and Colorectal Cancer Cells
Both 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F-203; NSC 703786) and 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW… 
2008
2008
BRCA1 modulates sensitivity to 5F-203 by regulating xenobiotic stress-inducible protein levels and EROD activity
PurposeWe have investigated the effects of BRCA1 over-expression and knockdown on 5F-203-induced gene expression and cytotoxicity… 
2006
2006
Differential Gene Expression as a Potential Classifier of 2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole-Sensitive and -Insensitive Cell Lines
2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole (5F-203) is a candidate antitumor agent empirically discovered with the aid of… 
2003
2003
Induction of CYP1A1 in tumor cells by the antitumor agent 2-[4-amino-3-methylphenyl]-5-fluoro-benzothiazole: a potential surrogate marker for patient sensitivity.
A candidate antitumor agent, 2-(4-amino-3-methylphenyl)-5-fluoro-benzothiazole (5F-203), like its non-fluorinated parent compound… 
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