5-nitroquinoline
National Institutes of Health
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Many promising drug candidates metabolized by aldehyde oxidase (AOX) fail during clinical trial owing to underestimation of their…
The syntheses and single crystal X-ray structures of [Ag(5-nitroquinoline)2]NO3 (1), [Ag(8-nitroquinoline)2]NO3·H2O (2), [Ag(6…
Background: NADPH:cytochrome P450 oxidoreductase (POR) catalyzes one-electron reduction of hypoxia-activated prodrugs (HAP…
Genotoxic nitrated polycyclic aromatic hydrocarbons (NPAHs) are formed during incomplete combustion processes by reaction of…
The formal [3+2] dipolar cycloaddition (or annulation) of donor-acceptor cyclopropanoate esters with pyridines and 5…
A reaction from various kinds of nitroquinoline with hydroxylamine in potassium hydroxide alkalinity produced a novel product…
The assessment of drugs designed to be useful in the eradication of hypoxic (resistant) cells involves comparison of hypoxic and…
The effects of a number of 4-nitroquinoline 1-oxide and 4-nitropyridine 1-oxide derivatives, with varying carcinogenic potencies…
Reactions of various substituted quinoline 1-oxides with cyanogen bromide in ethanol were investigated. The corresponding ethyl N…