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5-formamidoimidazole-4-carboxamide ribotide

Known as: FAICAR 
National Institutes of Health

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1 relation

Broader (1)

Ribonucleotides

Papers overview

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2007
2007
A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase.
Inosine 5'-monophosphate (IMP) cyclohydrolase catalyzes the cyclization of 5-formaminoimidazole-4-carboxamide ribonucleotide… 
1998
1998
Relationship between the catalytic sites of human bifunctional IMP synthase.
1994
1994
5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase from human CCRF-CEM leukemia cells: purification, pH dependence, and inhibitors.
The bifunctional enzyme 5-aminoimidazole-4-carboxamide ribotide (AICAR) transformylase-IMP cyclohydrolase has been purified 780… 
1994
1994
Radioassay of bifunctional 5-aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase by thin-layer chromatography.
A radioassay has been developed for the bifunctional enzyme, AICAR transformylase-IMP cyclohydrolase, which catalyzes reactions 9… 
1989
1989
Dual effects of pyrazofurin and 3-deazauridine upon pyrimidine and purine biosynthesis in mouse L1210 leukemia.
Pyrazofurin (NSC 143095) as the monophosphate derivative is a potent inhibitor of orotidine 5'-monophosphate (OMP) decarboxylase… 
1988
1988
106 PURINE NUCLEOTIDE RESTORATION IN HPRT− CELLS
Most metabolic therapies for HPRT deficiency have been aimed at restoring the nucleotide deficiency which is thought to occur as… 
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