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National Institutes of Health
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Characterization of a 5-HT3-ELIC Chimera Revealing the Sites of Action of Modulators.
S. C. Lummis
ACS chemical neuroscience
Corpus ID: 3706317
Cys-loop receptors are major sites of action for many important therapeutically active compounds, but the sites of action of…
Inhibitory effect of indole analogs against Paenibacillus larvae, the causal agent of American foulbrood disease
Journal of insect science
Corpus ID: 7957320
Abstract Paenibacillus larvae, a Gram-positive bacterium, causes American foulbrood (AFB) in honey bee larvae (Apis mellifera…
Investigation of the allosteric pharmacology of the 5-HT\(_3\) receptor identifying the potent allosteric modulator 5-chloroindole
Corpus ID: 82650639
The 5-HT\(_3\) receptor is a ligand-gated ion channel that mediates for example fast synaptic neurotransmission in the CNS and…
VIABILITY OF ENGINEERED BIOCATALYSTS IN BIOTRANSFORMATION BY LOUISE DAWN HACKETT A THESIS SUBMITTED TO THE UNIVERSITY OF BIRMINGHAM FOR THE DEGREE OF MASTER OF PHILOSOPHY SCHOOL OF CHEMICAL…
Corpus ID: 55185308
This project aims to exploit engineered biofilms as biocatalysts i n he biotransformations of enantiomerically pure compounds for…
5‐Chloroindole: a potent allosteric modulator of the 5‐HT3 receptor
Amy S. Newman
British journal of pharmacology
Corpus ID: 207096551
The 5‐HT3 receptor is a ligand‐gated ion channel that is modulated allosterically by various compounds including colchicine…
Reductive dechlorination of polychlorinated biphenyls as affected by natural halogenated aromatic compounds.
Journal of microbiology
Corpus ID: 22435876
We investigated the effects of halogenated aromatic compounds (HACs) including naturally occurring ones (L-thyroxine, 3-chloro-L…
N,N-Dialkylated 4-(4-arylsulfonylpiperazine-1-carbonyl)-benzamidines and 4-((4-arylsulfonyl)-2-oxo-piperazin-1-ylmethyl)-benzamidines as potent factor Xa inhibitors.
Bioorganic & medicinal chemistry letters
Corpus ID: 32164609
A class of N,N-dialkylated 4-(4-arylsulfonylpiperazine-1-carbonyl)-benzamidines and 4-((4-arylsulfonyl)-2-oxo-piperazin-1…
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