Skip to search formSkip to main contentSkip to account menu

5-carboxy-8-hydroxyquinoline

Known as: 8-hydroxy-5-quinolinecarboxylic acid, IOX1 compound 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Hydroxyquinolines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Novel 5-carboxy-8-HQ based histone demethylase JMJD2A inhibitors: introduction of an additional carboxyl group at the C-2 position of quinoline.
Highly Cited
2014
Highly Cited
2014
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.
In prostate cancer, two different types of histone lysine demethylases (KDM), LSD1/KDM1 and JMJD2/KDM4, are coexpressed and… 
Highly Cited
2014
Highly Cited
2014
A Cell-Permeable Ester Derivative of the JmjC Histone Demethylase Inhibitor IOX1
The 2‐oxoglutarate (2OG)‐dependent Jumonji C domain (JmjC) family is the largest family of histone lysine demethylases. There is… 
Highly Cited
2013
Highly Cited
2013
5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.
2-Oxoglutarate and iron dependent oxygenases are therapeutic targets for human diseases. Using a representative 2OG oxygenase… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)