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5-azacytosine

National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
A new solid-phase extraction adsorbent was prepared by employing a two-step "grafting from" approach to anchor a multidentate N… Expand
Review
2008
Review
2008
The cytosine analogues 5‐azacytosine (azacytidine) and 2′‐deoxy‐5‐azacytidine (decitabine) are the currently most advanced drugs… Expand
Highly Cited
2008
Highly Cited
2008
Decitabine (DAC) and 5-azacitidine have recently been approved for the treatment of myelodysplastic syndrome. The pharmacodynamic… Expand
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Review
2002
Review
2002
5-Azacytidine was first synthesized almost 40 years ago. It was demonstrated to have a wide range of anti-metabolic activities… Expand
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Highly Cited
1987
Highly Cited
1987
A clonal cell line (56-42) that was stably and exclusively resistant to the toxic effects of the antileukemic agent 5-aza-2… Expand
Highly Cited
1984
Highly Cited
1984
DNA containing 5-azacytosine (azaC) has previously been shown to be a potent inhibitor of DNA-cytosine methyltransferases. In… Expand
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Highly Cited
1982
Highly Cited
1982
Treatment of Friend erythroleukemia cells with the antileukemic drugs 5-azacytidine and 5-aza-2'-deoxycytidine leads to rapid… Expand
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Highly Cited
1982
Highly Cited
1982
Abstract Hemimethylated DNA substrates prepared from cell cultures treated with 5-azacytidine are efficient acceptors of methyl… Expand
Highly Cited
1981
Highly Cited
1981
Duplex heavy-light (HL) DNAs synthesized in the presence of brdUrd and methylation inhibitors were separated from bulk cellular… Expand
1979
1979
5-Azacytosine arabinoside (ara-AC) can be considered a combination of structural elements derived from the antitumor nucleosides… Expand