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5-azacytosine

 
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
A new solid-phase extraction adsorbent was prepared by employing a two-step "grafting from" approach to anchor a multidentate N… Expand
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Highly Cited
2008
Highly Cited
2008
Decitabine (DAC) and 5-azacitidine have recently been approved for the treatment of myelodysplastic syndrome. The pharmacodynamic… Expand
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2008
2008
1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine [HPMP-5-azaC], the 5-azacytosine analogue of cidofovir (HPMPC… Expand
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Highly Cited
1995
Highly Cited
1995
The mechanism of inhibition of DNA (cytosine-5-)-methyltransferases by the mechanism-based inhibitor 5-azacytosine has remained… Expand
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Highly Cited
1987
Highly Cited
1987
A clonal cell line (56-42) that was stably and exclusively resistant to the toxic effects of the antileukemic agent 5-aza-2… Expand
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Highly Cited
1984
Highly Cited
1984
DNA containing 5-azacytosine (azaC) has previously been shown to be a potent inhibitor of DNA-cytosine methyltransferases. In… Expand
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Highly Cited
1982
Highly Cited
1982
Treatment of Friend erythroleukemia cells with the antileukemic drugs 5-azacytidine and 5-aza-2'-deoxycytidine leads to rapid… Expand
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Highly Cited
1982
Highly Cited
1982
Hemimethylated DNA substrates prepared from cell cultures treated with 5-azacytidine are efficient acceptors of methyl groups… Expand
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Highly Cited
1981
Highly Cited
1981
Duplex heavy-light (HL) DNAs synthesized in the presence of brdUrd and methylation inhibitors were separated from bulk cellular… Expand
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1979
1979
5-Azacytosine arabinoside (ara-AC) can be considered a combination of structural elements derived from the antitumor nucleosides… Expand
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