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5-azacytosine

National Institutes of Health

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Broader (1)

Cytosine
analogs & derivatives

Papers overview

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2011
2011
The new 5- or 6-azapyrimidine and cyanuric acid derivatives of l-ascorbic acid bearing the free C-5 hydroxy or C-4 amino group at the ethylenic spacer: CD-spectral absolute configuration…
2006
2006
Reaction of hydroxyl radicals with azacytosines: a pulse radiolysis and theoretical study.
Pulse radiolysis and density functional theory (DFT) calculations at B3LYP/6-31+G(d,p) level have been carried out to probe the… 
Highly Cited
2002
Highly Cited
2002
Purification, Substrate Range, and Metal Center of AtzC: the N-Isopropylammelide Aminohydrolase Involved in Bacterial Atrazine Metabolism
ABSTRACT N-Isopropylammelide isopropylaminohydrolase, AtzC, the third enzyme in the atrazine degradation pathway in Pseudomonas… 
1995
1995
Cytosine methyltransferase from Escherichia coli in which active site cysteine is replaced with serine is partially active.
EcoRII methyltransferase (M.EcoRII) catalyzes the transfer of methyl groups from S-adenosyl-L-methionine (SAM) to C-5 position of… 
Review
1994
Review
1994
Biological implications of the mechanism of action of human DNA (cytosine-5)methyltransferase.
1989
1989
Rapid induction of genomic demethylation and T-DNA gene expression in plant cells by 5-azacytosine derivatives
We have optimized conditions for demethylation of the genome and induction of a silent, hypermethylated T-DNA gene (ipt) by 5… 
Highly Cited
1987
Highly Cited
1987
Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance
A clonal cell line (56-42) that was stably and exclusively resistant to the toxic effects of the antileukemic agent 5-aza-2… 
Highly Cited
1987
Highly Cited
1987
Nucleotide sequence and expression of the gene encoding the EcoRII modification enzyme
The gene coding for the EcoRII modification enzyme has been cloned and the nucleotide sequence of 1933 base pairs containing the… 
1984
1984
Development of an intravenous formulation for the unstable investigational cytotoxic nucleosides 5‐azacytosine arabinoside (NSC 281272) and 5‐azacytidine (NSC 102816)
In aqueous solutions 5‐azacytosine arabinoside (aza‐A) (NSC 281272) exhibits complex and rapid degradation of a type analogous to… 
1979
1979
Synthesis and antitumor activity of 5-azacytosine arabinoside.
5-Azacytosine arabinoside (ara-AC) can be considered a combination of structural elements derived from the antitumor nucleosides… 
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