5-Aminolevulinate Synthase, Nonspecific, Mitochondrial

Known as: 5-Aminolevulinic Acid Synthase 1, Migration-Inducing Protein 4, EC 2.3.1.37 
5-aminolevulinate synthase, nonspecific, mitochondrial (640 aa, ~71 kDa) is encoded by the human ALAS1 gene. This protein plays a role in both… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2015
02419742015

Papers overview

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2010
2010
The rate of porphyrin biosynthesis in mammals is controlled by the activity of the pyridoxal 5'-phosphate-dependent enzyme 5… (More)
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2000
2000
Reactive oxygen species are thought to be involved in the pathogenesis of septic multiple organ dysfunction syndrome (MODS). It… (More)
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1998
1998
5-Aminolevulinate synthase (EC 2.3.1.37) catalyzes the first reaction in the heme biosynthetic pathway in nonplant eukaryotes and… (More)
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1995
1995
Rhodobacter sphaeroides H-5 was isolated as a 5-aminolevulinic acid (ALA) auxotroph following treatment of wild-type cells with N… (More)
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1989
1989
A controversy has existed in the literature for the past several years regarding the number of vertebrate genes encoding the… (More)
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1988
1988
The metabolism of heme is impaired in lymphocytes of patients with malignant lymphoproliferative disorders (MLPO). Two of the… (More)
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1986
1986
Previous studies of legume nodules have indicated that formation of the heme moiety of leghemoglobin is a function of the… (More)
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1985
1985
We report the isolation of cDNA clones encoding delta-aminolevulinate synthase (ALA synthase; EC 2.3.1.37), the first enzyme in… (More)
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1979
1979
1. Treatment of rats with small doses of CoCl2 decreases liver 5-aminolaevulinate synthase (EC 2.3.1.37) activity and impairs… (More)
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1975
1975
The customary route in animals and bacteria for delta-aminolevulinic acid biosynthesis is from glycine and succinyl CoA… (More)
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